Swallowing Training in Parkinson`s Disease
This study has been completed.
Sponsor:
Federal University of Bahia
Information provided by (Responsible Party):
Natalie Argolo Pereira Ponte, Federal University of Bahia
ClinicalTrials.gov Identifier:
NCT01131494
First received: May 25, 2010
Last updated: October 4, 2011
Last verified: October 2011
- Full Text View
- Tabular View
- Study Results
- Disclaimer
- How to Read a Study Record
Purpose
Dysphagia in Parkinson's disease(PD) is common and its presence is related to motor and sensory abnormalities, and incoordination between swallowing and breathing. Despite harming as respiratory infections and increased risk of death, treatment of this condition remains uncertain. This study aims to evaluate the effect of oral motor exercises on the swallowing dynamics and quality of life of dysphagic Parkinson's disease patients. This study is an open trial, self-paired and blinded to the examiner. The participants will perform oropharyngeal exercises for five weeks and will be evaluated before and after intervention by swallowing videofluoroscopy and questionnaires about quality of life in dysphagia (SWAL-QOL).
| Condition | Intervention |
|---|---|
|
Parkinson's Disease Deglutition Disorders Voice Disorders |
Other: Motor exercises for swallowing, breathing and phonation |
| Study Type: | Interventional |
| Study Design: | Endpoint Classification: Efficacy Study Intervention Model: Single Group Assignment Masking: Single Blind (Outcomes Assessor) Primary Purpose: Treatment |
| Official Title: | Dysphagia Therapy for Parkinson`s Disease: the Role of the Oral Motor Exercises |
Resource links provided by NLM:
MedlinePlus related topics:
Exercise and Physical Fitness
Parkinson's Disease
Swallowing Disorders
Voice Disorders
U.S. FDA Resources
Further study details as provided by Federal University of Bahia:
Primary Outcome Measures:
- Oropharyngeal Swallowing Score [ Time Frame: five weeks ] [ Designated as safety issue: No ]Based on videofluoroscopy, were awarded points for the swallowing events according to their clinical relevance. The sum of these points results in the OSP (Oropharyngeal Swallowing Score), so that higher scores signify greater impairment in swallowing. OSP-score range from 0 to 243.5. This tool is being validated for that group.
Secondary Outcome Measures:
- Quality of Life [ Time Frame: five weeks ] [ Designated as safety issue: No ]Measured by the Swal-qol (Quality of life in Swallowing disorders). In this questionnaire the score range from 0 to 100 and higher scores is better quality of life.
| Enrollment: | 17 |
| Study Start Date: | March 2009 |
| Study Completion Date: | December 2010 |
| Primary Completion Date: | October 2010 (Final data collection date for primary outcome measure) |
| Arms | Assigned Interventions |
|---|---|
| Experimental: Swallowing exercises |
Other: Motor exercises for swallowing, breathing and phonation
This exercises aimed to increase strength and range of motion of mouth, larynx and pharynx structures. All patients made sustained vowel phonation of /a/, pushing plosive phonemes /pa/, /ta/, /ka/ in a forceful manner, suction of wet gauze, swallowing with tongue hold and modified supraglottic maneuver, in ten repetitions, ascending and descending gliding phonation of vowel /a/ and /u/, five repetitions of each vowel, and tongue rotation in oral vestibule, 3 series of 5 repetitions to each side. Patients underwent oral motor exercises twice a day, five days a week, for five weeks.
|
Eligibility| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
Criteria
Inclusion Criteria:
- Clinical diagnosis of Parkinson disease
- Complaint of dysphagia
Exclusion Criteria:
- Hoehn and Yahr stage 5
- Other neurological conditions
- Therapy for swallowing in the last 3 months
- Cognitive disorders
- Psychiatric disorders
Contacts and Locations More Information
No publications provided
| Responsible Party: | Natalie Argolo Pereira Ponte, PhD Student, Federal University of Bahia |
| ClinicalTrials.gov Identifier: | NCT01131494 History of Changes |
| Other Study ID Numbers: | 249/2008 |
| Study First Received: | May 25, 2010 |
| Results First Received: | May 5, 2011 |
| Last Updated: | October 4, 2011 |
| Health Authority: | Brazil: Ministry of Health |
Keywords provided by Federal University of Bahia:
|
Parkinson's disease Dysphagia Treatment |
Additional relevant MeSH terms:
|
Deglutition Disorders Parkinson Disease Voice Disorders Esophageal Diseases Gastrointestinal Diseases Digestive System Diseases Pharyngeal Diseases Otorhinolaryngologic Diseases Parkinsonian Disorders Basal Ganglia Diseases |
Brain Diseases Central Nervous System Diseases Nervous System Diseases Movement Disorders Neurodegenerative Diseases Laryngeal Diseases Respiratory Tract Diseases Neurologic Manifestations Signs and Symptoms |
ClinicalTrials.gov processed this record on May 23, 2013