Effect of Prolonged Military Exercises With High Load Carriage, on Neuromuscular Fatigue and Physiological/Biomechanical Responses

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Centre Hospitalier Universitaire de Saint Etienne
ClinicalTrials.gov Identifier:
NCT01127191
First received: May 11, 2010
Last updated: July 24, 2012
Last verified: July 2012
  Purpose

Land military missions generally combine prolonged walking/moderate-pace-running and other physical actions such as creeping, jumping, shooting,… which are associated with the direct carrying of high to severe loads of equipment and supplies (20-30 to 50 kg) by soldiers. For an infantry section, "typical" intervention phases last about 20-24 h and combine variable intensity grades. Consequently, military mission characteristics are an interesting investigation field of human fatigue. Previous studies have investigated human neuromuscular alterations after prolonged "normal" locomotion exercises [Millet et al., 2004, 2009], thus the aim of this study is to characterize the neuromuscular determinants of fatigue induced by a 24-h Simulated Military Effort (SME) and a 4-h Military Road March (MM), both performed with high load carriage. Additionally, the consequences of fatigue on physiological and biomechanical parameters of locomotion will be investigated.


Condition Intervention
Healthy
Other: military equipment

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective

Resource links provided by NLM:


Further study details as provided by Centre Hospitalier Universitaire de Saint Etienne:

Primary Outcome Measures:
  • Central fatigue quantification based on voluntary and electrically-induced force measurement on activated muscle. [ Time Frame: after a a military exercise of 24 hours ] [ Designated as safety issue: No ]
  • Peripheral fatigue based on electrically-induced force measurement on the same muscle in relaxed condition. [ Time Frame: after a a military exercise of 24 hours ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Oxygen uptake, carbon-dioxide output, energetic-cost of locomotion and respiratory ratio, based on subject's gas exchanges. [ Time Frame: after a a military exercise of 24 hours ] [ Designated as safety issue: No ]
  • Lactatemia, based on subject's arterialized capillary blood samples analysis [ Time Frame: after a a military exercise of 24 hours ] [ Designated as safety issue: No ]
  • Muscular electrical activities, based on subject's surface EMG analysis [ Time Frame: after a a military exercise of 24 hours ] [ Designated as safety issue: No ]
  • Heart rate frequence [ Time Frame: after a a military exercise of 24 hours ] [ Designated as safety issue: No ]
  • Walking and running mechanics, measured by an instrumented treadmill [ Time Frame: after a a military exercise of 24 hours ] [ Designated as safety issue: No ]
  • Postural equilibration, measured by a piezo-dynamometric double platform [ Time Frame: after a a military exercise of 24 hours ] [ Designated as safety issue: No ]
  • Rate of perceived exertion, measured by the Borg scale ranging from 6 to 20 [ Time Frame: after a a military exercise of 24 hours ] [ Designated as safety issue: No ]
  • Perceived comfort, measured by a 10 cm visual analogic scale (VAS) [ Time Frame: after a a military exercise of 24 hours ] [ Designated as safety issue: No ]

Biospecimen Retention:   Samples Without DNA

Lactatemia, based on subject's arterialized capillary blood samples analysis.


Enrollment: 10
Study Start Date: March 2010
Study Completion Date: April 2010
Primary Completion Date: April 2010 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
Military Other: military equipment
Military exercise of 24 hours

  Eligibility

Ages Eligible for Study:   30 Years to 45 Years
Genders Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population

military retreated from national army

Criteria

Inclusion Criteria:

  • to be a male
  • to have a VO2max > 45ml/min/kg (mean observed value in military subjects)
  • to be aged from 30 to 45
  • to be recently retreated from National Army
  • to be highly experienced in military efforts
  • to be trained in exercises involving load carrying
  • to benefit from a social security insurance

Exclusion Criteria:

  • All subjects with recent (< 3 month) bone, articular or muscle diseases.
  • All subjects presenting a clinic sign of intolerance to testing procedures, especially subjects with knee, ankle, hip or back diseases.
  • All subjects intolerant to muddy or wooded environment.
  • All subjects presenting a clinic sign of intolerance to exercise, and particularly to running or walking while carrying a load
  • All subjects involved at the same time in another medical research
  • All subjects militarily active
  • All subjects with cardiac or pulmonary identified and known diseases
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01127191

Locations
France
CHU de Saint-Etienne
Saint-Etienne, France, 42055
Sponsors and Collaborators
Centre Hospitalier Universitaire de Saint Etienne
Investigators
Principal Investigator: Roger OULLION, Dr CHU SAINT-ETIENNE
  More Information

No publications provided by Centre Hospitalier Universitaire de Saint Etienne

Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: Centre Hospitalier Universitaire de Saint Etienne
ClinicalTrials.gov Identifier: NCT01127191     History of Changes
Other Study ID Numbers: 0901110, 2009-A01346-51
Study First Received: May 11, 2010
Last Updated: July 24, 2012
Health Authority: France: Afssaps - Agence française de sécurité sanitaire des produits de santé (Saint-Denis)

Keywords provided by Centre Hospitalier Universitaire de Saint Etienne:
military exercises
neuromuscular fatigue
physiological responses
biomechanical responses
simulated military effort
high load carriage
Healthy voluntary

ClinicalTrials.gov processed this record on October 20, 2014