Chronic and Acute Effects of Resistance Exercise on Older Subjects' Blood Pressure (RTBP)

This study has been completed.
Sponsor:
Collaborators:
Conselho Nacional de Desenvolvimento Científico e Tecnológico
Fundação de Amparo à Pesquisa do Estado de São Paulo
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.
Associacao Fundo de Incentivo a Psicofarmcologia
Federal University of São Paulo
Delboni Auriemo
Information provided by:
University of Sao Paulo
ClinicalTrials.gov Identifier:
NCT01113203
First received: April 27, 2010
Last updated: April 28, 2010
Last verified: April 2010
  Purpose

The study aimed to evaluate the chronic and acute effects of high-intensity resistance training on blood pressure and its hemodynamic and neural determinators in healthy normotensive older subjects.


Condition Intervention
Blood Pressure
Behavioral: Resistance training

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Prevention
Official Title: Chronic and Acute Effects of Resistance Exercise on Older Subjects' Blood Pressure

Resource links provided by NLM:


Further study details as provided by University of Sao Paulo:

Primary Outcome Measures:
  • blood pressure [ Time Frame: 16 weeks ] [ Designated as safety issue: Yes ]
    Blood pressure was measured by auscultatory, oscillometric and photoplethysmographic device


Secondary Outcome Measures:
  • cardiovascular hemodynamics [ Time Frame: 16 weeks ] [ Designated as safety issue: Yes ]
    cardiac output (CO2 rebreathing technique)

  • cardiovascular autonomic modulation [ Time Frame: 16 weeks ] [ Designated as safety issue: Yes ]
    Spectral analysis of heart rate and blood pressure variabillity


Enrollment: 25
Study Start Date: January 2008
Study Completion Date: December 2008
Primary Completion Date: December 2008 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Resistance training
Progressive high intensity resistance training performed twice a week for 16 weeks, and achieving in 7 exercises for the main muscles, the protocol of 4 sets of 6RM and 2 of 4RM.
Behavioral: Resistance training
Progressive high intensity resistance training performed twice a week for 16 weeks, and achieving in 7 exercises for the main muscles, the protocol of 4 sets of 6RM and 2 of 4RM.
Other Name: strength training, weight training

Detailed Description:

To investigate the chronic and acute effects of resistance training on blood pressure and its hemodynamic and neural determinators in elderly, 24 healthy normotensive older subjects were randomly divided into 2 groups: trained and control. The trained group was submitted a progressive high-intensity resistance training. Before and after 16 weeks, as well as, before and after the one training session, blood pressure (clinic and ambulatory), cardiac output (CO2 rebreathing), and autonomic modulation (spectral analysis of heart rate and blood pressure variabilities) were measured

  Eligibility

Ages Eligible for Study:   60 Years to 80 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Age 60 to 80 years
  • Normotensives
  • Nonactive

Exclusion Criteria:

  • Cardiovascular disease
  • Cardiovascular medication
  • Orthopedic problems
  Contacts and Locations
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Please refer to this study by its ClinicalTrials.gov identifier: NCT01113203

Locations
Brazil
School of Physical Education and Sport, University of São Paulo
São Paulo, SP, Brazil, 05508-030
Sponsors and Collaborators
University of Sao Paulo
Conselho Nacional de Desenvolvimento Científico e Tecnológico
Fundação de Amparo à Pesquisa do Estado de São Paulo
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.
Associacao Fundo de Incentivo a Psicofarmcologia
Federal University of São Paulo
Delboni Auriemo
Investigators
Principal Investigator: Claudia LM Forjaz, PhD School of Physical Education and Sport, University of São Paulo
  More Information

No publications provided by University of Sao Paulo

Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: Cláudia Lúcia de Moraes Forjaz, School of Physical Education, University of São Paulo
ClinicalTrials.gov Identifier: NCT01113203     History of Changes
Other Study ID Numbers: CNPq471600/2008-3
Study First Received: April 27, 2010
Last Updated: April 28, 2010
Health Authority: Brazil: National Committee of Ethics in Research

Keywords provided by University of Sao Paulo:
resistance training
blood pressure
hemodynamics
autonomic
Elderly Subjects

ClinicalTrials.gov processed this record on September 18, 2014