Vasopressin Deficiency in Hemorrhagic Shock
In this study we hope to delineate the typical vasoactive mediator response of trauma patients to shock. We plan to assess serum levels of vasopressin and also catecholamines, angiotensin, and cortisol during resuscitation of trauma patients to delineate high risk populations for vasopressin deficiency.
|Study Design:||Time Perspective: Prospective|
|Official Title:||Vasopressin Deficiency in Hemorrhagic Shock|
|Study Start Date:||February 2010|
|Study Completion Date:||April 2011|
SBP less than 90mmHg
Blood draws (total 48 cc blood)
This is a prospective observational study. The only research-driven procedure will be the removal of blood samples at designated time points(total blood removed 48 cc per patient). Hemodynamic, fluid infusion and agitation/pain data (RAMSEY Score) will prospectively be collected for research purposes. We will collect data from a convenience sample of patients (when research staff is available) over a one year period.
|United States, Texas|
|San Antonio, Texas, United States, 78229-3900|
|Principal Investigator:||Stephen M Cohn, MD||The University of Texas Health Science Center at San Antonio|