The Neuroeconomics of Behavioral Therapies for Adolescent Substance Abuse (Imaging)
This study is currently recruiting participants.
Verified November 2012 by Dartmouth-Hitchcock Medical Center
Sponsor:
Dartmouth-Hitchcock Medical Center
Collaborator:
Information provided by (Responsible Party):
Dartmouth-Hitchcock Medical Center
ClinicalTrials.gov Identifier:
NCT01093898
First received: March 23, 2010
Last updated: November 2, 2012
Last verified: November 2012
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Purpose
This study will measure the brain activity of adolescent substance abusers while they make decisions about their preferences to receive smaller, immediate rewards versus larger delayed rewards. The investigators expect that patterns of brain activity while engaged in this decision making task will predict response to treatment among adolescent substance users. The investigators expect to use the results of this study to develop more effective treatments for adolescent substance abuse
| Condition |
|---|
|
Adolescent Substance Use |
| Study Type: | Observational |
| Study Design: | Observational Model: Family-Based Time Perspective: Prospective |
| Official Title: | The Neuroeconomics of Behavioral Therapies for Adolescent Substance Abuse |
Further study details as provided by Dartmouth-Hitchcock Medical Center:
Primary Outcome Measures:
- Marijuana and alcohol abstinence [ Time Frame: Assessed at end of treatment, and quarterly for one year after treatment ] [ Designated as safety issue: No ]
| Estimated Enrollment: | 123 |
| Study Start Date: | April 2010 |
| Estimated Study Completion Date: | March 2013 |
| Estimated Primary Completion Date: | March 2013 (Final data collection date for primary outcome measure) |
| Groups/Cohorts |
|---|
| No intervention |
Show Detailed Description Eligibility| Ages Eligible for Study: | 12 Years to 18 Years |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | Yes |
| Sampling Method: | Non-Probability Sample |
Study Population
Adolescents recruited into the Marijuana Trial and the Alcohol Trial during the period of the R21 project would participate in a single neuroimaging session as soon after the intake session as possible.
Criteria
Inclusion Criteria:
- Participants must be 12 to 18 years old and have a parent/guardian who can participate.
Youth must meet either of the following inclusion criteria:
- Report using marijuana during the previous 30 days or provide a marijuana-positive urine test, plus meet criteria for Cannabis Abuse or Dependence OR
- Meet DSM criteria for Alcohol Abuse or dependence or have had one binge episode, specified by ≥5 drinks in one day, in the past 90 days and report alcohol use in the past 30 days.
Exclusion Criteria:
- Contraindications to MRI including ferromagnetic implants or claustrophobia
- Meeting DSM criteria for dependence on illicit drugs other than marijuana or alcohol (use/abuse of other drugs will not be excluded)
- Exhibit active psychosis, have severe medical or psychiatric illness limiting participation
- Are pregnant or breast-feeding.
Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01093898
Contacts
| Contact: Catherine Stanger, Ph.D. | 855 290 2822 | catherine.stanger@dartmouth.edu |
| Contact: Alan J Budney, Ph.D. | 855 290 2822 | alan.j.budney@dartmouth.edu |
Locations
| United States, New Hampshire | |
| Geisel School of Medicine at Dartmouth | Recruiting |
| Lebanon, New Hampshire, United States, 03756 | |
| Contact: Gray Norton 855-290-2822 gray.e.norton@dartmouth.edu | |
| Contact: Leanna M Delhey 855 290 2822 leanna.m.delhey@dartmouth.edu | |
| Principal Investigator: Catherine Stanger, Ph.D. | |
| Sub-Investigator: Alan J Budney, PhD | |
| Sub-Investigator: Robert Roth, PhD | |
Sponsors and Collaborators
Dartmouth-Hitchcock Medical Center
Investigators
| Principal Investigator: | Catherine Stanger, Ph.D. | Geisel School of Medicine at Dartmouth |
More Information
No publications provided
| Responsible Party: | Dartmouth-Hitchcock Medical Center |
| ClinicalTrials.gov Identifier: | NCT01093898 History of Changes |
| Other Study ID Numbers: | 36824, 1 R21 DA029442-01 |
| Study First Received: | March 23, 2010 |
| Last Updated: | November 2, 2012 |
| Health Authority: | United States: Institutional Review Board |
Additional relevant MeSH terms:
|
Substance-Related Disorders Mental Disorders |
ClinicalTrials.gov processed this record on May 23, 2013