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Adipose Expression of Leptin, Adiponectin and IL-6 and Plasma Levels of Adipocytokines in Women With and Without Polycystic Ovary Syndrome (PCOS)

This study has been completed.
Sponsor:
Collaborators:
Aarhus University Hospital
Statens Serum Institute
Information provided by:
Copenhagen University Hospital, Hvidovre
ClinicalTrials.gov Identifier:
NCT01088061
First received: March 16, 2010
Last updated: October 27, 2011
Last verified: January 2008
History of Changes
  Purpose

The purpose of the study was to investigate adipose expression and plasma levels of different adipocytokine, which may play a role in the pathophysiology of PCOS. The investigators investigated lean and obese women with and without PCOS.


Condition
Polycystic Ovary Syndrome

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Cross-Sectional
Official Title: Adipocytokines in Lean and Obese Women With and Without PCOS

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by Copenhagen University Hospital, Hvidovre:

Primary Outcome Measures:
  • Adipose expression of adipocytokines [ Time Frame: From February 2004 -April 2006 ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Plasma levels of adipocytokines [ Time Frame: From February 2004-April 2006 ] [ Designated as safety issue: No ]

Biospecimen Retention:   Samples With DNA

Fat biopsies, plasma


Enrollment: 65
Study Start Date: January 2004
Study Completion Date: April 2006
Primary Completion Date: April 2006 (Final data collection date for primary outcome measure)
Groups/Cohorts
lean women with PCOS
Obese women with PCOS
lean control women
Obese control women

  Eligibility

Ages Eligible for Study:   18 Years to 40 Years
Genders Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

Lean and obese women with and without PCOS, age 18-40 years.

Criteria

Inclusion Criteria:

  • women with PCOS according to the Rotterdam criteria

Exclusion Criteria:

  • other known diseases
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01088061

Locations
Denmark
Copenhagen University Hospital, Hvidovre
Hvidovre, Denmark, 1650
Sponsors and Collaborators
Copenhagen University Hospital, Hvidovre
Aarhus University Hospital
Statens Serum Institute
Investigators
Principal Investigator: Pernille Fog Svendsen, MD Copenhagen University Hospital, Hvidovre
  More Information

No publications provided

Responsible Party: Copenhagen University Hospital, Hvidovre, Hospital
ClinicalTrials.gov Identifier: NCT01088061     History of Changes
Other Study ID Numbers: pcos0509
Study First Received: March 16, 2010
Last Updated: October 27, 2011
Health Authority: Denmark: National Board of Health

Additional relevant MeSH terms:
Polycystic Ovary Syndrome
Ovarian Cysts
Cysts
Neoplasms
Ovarian Diseases
 Adnexal Diseases
Genital Diseases, Female
Gonadal Disorders
Endocrine System Diseases

ClinicalTrials.gov processed this record on May 19, 2013