Adipose Expression of Leptin, Adiponectin and IL-6 and Plasma Levels of Adipocytokines in Women With and Without Polycystic Ovary Syndrome (PCOS)

This study has been completed.
Sponsor:
Collaborators:
Aarhus University Hospital
Statens Serum Institut
Information provided by:
Copenhagen University Hospital, Hvidovre
ClinicalTrials.gov Identifier:
NCT01088061
First received: March 16, 2010
Last updated: October 27, 2011
Last verified: January 2008
  Purpose

The purpose of the study was to investigate adipose expression and plasma levels of different adipocytokine, which may play a role in the pathophysiology of PCOS. The investigators investigated lean and obese women with and without PCOS.


Condition
Polycystic Ovary Syndrome

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Cross-Sectional
Official Title: Adipocytokines in Lean and Obese Women With and Without PCOS

Resource links provided by NLM:


Further study details as provided by Copenhagen University Hospital, Hvidovre:

Primary Outcome Measures:
  • Adipose expression of adipocytokines [ Time Frame: From February 2004 -April 2006 ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Plasma levels of adipocytokines [ Time Frame: From February 2004-April 2006 ] [ Designated as safety issue: No ]

Biospecimen Retention:   Samples With DNA

Fat biopsies, plasma


Enrollment: 65
Study Start Date: January 2004
Study Completion Date: April 2006
Primary Completion Date: April 2006 (Final data collection date for primary outcome measure)
Groups/Cohorts
lean women with PCOS
Obese women with PCOS
lean control women
Obese control women

  Eligibility

Ages Eligible for Study:   18 Years to 40 Years
Genders Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

Lean and obese women with and without PCOS, age 18-40 years.

Criteria

Inclusion Criteria:

  • women with PCOS according to the Rotterdam criteria

Exclusion Criteria:

  • other known diseases
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01088061

Locations
Denmark
Copenhagen University Hospital, Hvidovre
Hvidovre, Denmark, 1650
Sponsors and Collaborators
Copenhagen University Hospital, Hvidovre
Aarhus University Hospital
Statens Serum Institut
Investigators
Principal Investigator: Pernille Fog Svendsen, MD Copenhagen University Hospital, Hvidovre
  More Information

No publications provided

Responsible Party: Copenhagen University Hospital, Hvidovre, Hospital
ClinicalTrials.gov Identifier: NCT01088061     History of Changes
Other Study ID Numbers: pcos0509
Study First Received: March 16, 2010
Last Updated: October 27, 2011
Health Authority: Denmark: National Board of Health

Additional relevant MeSH terms:
Polycystic Ovary Syndrome
Ovarian Cysts
Cysts
Neoplasms
Ovarian Diseases
Adnexal Diseases
Genital Diseases, Female
Gonadal Disorders
Endocrine System Diseases

ClinicalTrials.gov processed this record on July 28, 2014