Stiffness of the Skin and Joints in Relation to Carpal Tunnel Syndrome (STIF-CTS)

The recruitment status of this study is unknown because the information has not been verified recently.
Verified April 2010 by St. Antonius Hospital.
Recruitment status was  Not yet recruiting
Sponsor:
Information provided by:
St. Antonius Hospital
ClinicalTrials.gov Identifier:
NCT01081860
First received: March 2, 2010
Last updated: April 26, 2010
Last verified: April 2010
  Purpose

The exact etiology of CTS remains yet unknown. A rise in carpal tunnel pressure is well documented, but why this phenomenon occurs is yet unknown in most patients. There is an absolute or relative narrowing of the carpal tunnel, which results in a compression of the median nerve.

The investigators postulate, that a stiffer flexor retinaculum (roof of carpal tunnel) will be less compliant. As a consequence of this stiffer retinaculum the pressure in the carpal tunnel will rise more quickly in stiff patients resulting in CTS-complaints.

A relation between connective tissue composition and joint stiffness is proven. This relationship possibly extends to a relation between stiffness of the skin, joint stiffness and the prevalence of CTS.


Condition
Carpal Tunnel Syndrome

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Cross-Sectional
Official Title: Correlation of Joint Stiffness and Stiffness of the Skin and the Prevelation of Carpal Tunnel Syndrome (CTS)

Resource links provided by NLM:


Further study details as provided by St. Antonius Hospital:

Primary Outcome Measures:
  • Joint stiffness [ Time Frame: In the 1st month ] [ Designated as safety issue: No ]
    The active range of motion (elbow, wrist, knee and ankle) is measured with a standard goniometer.

  • Stiffness of the skin [ Time Frame: in the 1st month ] [ Designated as safety issue: No ]
    Skinstiffness is measured with a suction cup


Secondary Outcome Measures:
  • Physical activities [ Time Frame: In the 1st month ] [ Designated as safety issue: No ]
    Boston Questionairre


Estimated Enrollment: 40
Study Start Date: May 2010
Estimated Study Completion Date: December 2010
Estimated Primary Completion Date: November 2010 (Final data collection date for primary outcome measure)
Groups/Cohorts
Carpal tunnel syndrome
Patients with carpal tunnel syndrome
Trigger finger
Patients with trigger fingers
Dupuytren Contracture
Patients with Dupuytren
Trauma to the hand
Patients with an acute trauma to the hand

  Eligibility

Ages Eligible for Study:   18 Years to 60 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

Patients presenting with complaints of:

  • Carpal tunnel syndrome
  • Trigger finger
  • Dupuytren contracture
  • an acute trauma to the hand
Criteria

Inclusion Criteria:

  • Caucasian
  • Carpal tunnel release OR Trigger finger OR Dupuytren OR an acute trauma to the hand

Exclusion Criteria:

  • Hypo-/hyperthyroidism
  • Diabetes
  • Arthritis
  • Pregnancy
  • Obesity (BMI >30)
  • Anatomical anomalies
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01081860

Contacts
Contact: Bo Verwer b.verwer@antoniusziekenhuis.nl

Locations
Netherlands
St Antonius Hospital Not yet recruiting
Nieuwegein, Utrecht, Netherlands, 3430EM
Contact: Bo Verwer       b.verwer@antoniusziekenhuis.nl   
Sponsors and Collaborators
St. Antonius Hospital
Investigators
Principal Investigator: A.B. Mink van der Molen, dr. St. Antonius Hospital
  More Information

No publications provided

Responsible Party: dr. A.B. Mink van der Molen, department of plastic surgery St Antonius Hospital
ClinicalTrials.gov Identifier: NCT01081860     History of Changes
Other Study ID Numbers: STIF CTS
Study First Received: March 2, 2010
Last Updated: April 26, 2010
Health Authority: Netherlands: The Central Committee on Research Involving Human Subjects (CCMO)

Keywords provided by St. Antonius Hospital:
Carpal tunnel syndrome
CTS
Skinstiffness
Jointstiffness

Additional relevant MeSH terms:
Carpal Tunnel Syndrome
Syndrome
Cumulative Trauma Disorders
Disease
Median Neuropathy
Mononeuropathies
Nerve Compression Syndromes
Nervous System Diseases
Neuromuscular Diseases
Pathologic Processes
Peripheral Nervous System Diseases
Sprains and Strains
Wounds and Injuries

ClinicalTrials.gov processed this record on October 21, 2014