Clinical Pharmacists Role in the Management of Hypertension in Jordan

This study has been completed.
Sponsor:
Collaborator:
Jordan Hospital
Information provided by:
University of Jordan
ClinicalTrials.gov Identifier:
NCT01079494
First received: March 2, 2010
Last updated: April 6, 2010
Last verified: March 2009
  Purpose

Background: studies have demonstrated the crucial role of clinical pharmacists as integrated part of heath care team. Not only in Jordan but also in the Middle East region, clinical pharmacy practice is not well established. This current study is the first to evaluate physicians - pharmacists' collaborative approach to uncontrolled blood pressure in Jordan and the Middle East.


Condition Intervention
Hypertension
Other: pharmaceutical care services

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single Blind (Subject)
Primary Purpose: Health Services Research
Official Title: Clinical Pharmacists Role in the Management of Hypertension in Jordan

Resource links provided by NLM:


Further study details as provided by University of Jordan:

Primary Outcome Measures:
  • percentage of patients who achieved blood pressure goals specified by the JNC VII at each group [ Time Frame: 6 month ] [ Designated as safety issue: No ]
    defined a goal to be achieved if the systolic blood pressure fell below 140 mm Hg and the diastolic blood pressure fell below 90 mm Hg. Or systolic blood pressure fell below 130 mm Hg and the diastolic blood pressure fell below 80 mm Hg if patient was diabetic.


Secondary Outcome Measures:
  • mean reductions in both systolic and diastolic blood pressure readings [ Time Frame: 6 months ] [ Designated as safety issue: No ]
    mean reductions in systolic blood pressure (Systolic blood pressure at enrollment - Systolic blood pressure last follow up visit) and diastolic BP (Diastolic blood pressure at enrollment - Diastolic blood pressure last follow up visit) for both study groups


Enrollment: 266
Study Start Date: March 2009
Study Completion Date: November 2009
Primary Completion Date: November 2009 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Active Comparator: intervention group
physician-pharmacist teamwork
Other: pharmaceutical care services
Patients treatment related problems and therapeutic needs or complains identified by clinical pharmacist and managed collaboratively by both pharmacist and the physician.
No Intervention: control
physician only team

Detailed Description:

Objective: this study aimed to evaluate clinical pharmacists' role in the management of uncontrolled hypertensive patients in Jordan. Design: single blinded randomized controlled clinical trial. Patients: 253 patients with uncontrolled hypertension specified as higher blood pressure readings than the recommended goals by the seventh report of the Joint National Committee on prevention, detection, evaluation, and treatment of high blood pressure (JNC VII) at the time of enrollment.

Interventions: patients were randomly allocated to an intervention or control group: 130 and 123 patients, respectively. Patients in both arms were followed up for 6 months. In the intervention group, patients were managed by physician-clinical pharmacist team. In the control group, patients were managed by physician(s) only and were not provided pharmaceutical care services.

  Eligibility

Ages Eligible for Study:   21 Years to 88 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Patients with uncontrolled BP, receiving 0-3 antihypertensive drugs with no change in the regimen or dose within the past 3 month.

Exclusion Criteria:

  • Patients with hypertensive urgency or emergency with BP more than (180/110).
  • Patients with recent stroke or myocardial infraction (within past 6 months).
  • Patients with Class III or IV Chronic heart Failure (CHF).
  • Patients with Unstable angina.
  • Patients with Serious renal or hepatic disease.
  • Pregnant patients.
  • Patients with Dementia or cognitive impairment.
  • If the patient is unable to provide informed written consent.
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01079494

Locations
Jordan
family medicine clinic JUH
Amman, Jordan, 13046
Sponsors and Collaborators
University of Jordan
Jordan Hospital
Investigators
Principal Investigator: Eman Hammad, MSc University of Jordan/ Faculty of Pharmacy
Study Director: Abla Al bsoul, PhD University of Jordan/ Faculty of Pharmacy
  More Information

No publications provided

Responsible Party: Eman Hammad, faculty of pharmacy / University of Jordan
ClinicalTrials.gov Identifier: NCT01079494     History of Changes
Other Study ID Numbers: JU8071383
Study First Received: March 2, 2010
Last Updated: April 6, 2010
Health Authority: Jordan: Ethical Committee

Keywords provided by University of Jordan:
Uncontrolled blood pressure

Additional relevant MeSH terms:
Hypertension
Vascular Diseases
Cardiovascular Diseases

ClinicalTrials.gov processed this record on April 17, 2014