Coffee Trial - Does Coffee Intake Reduce Postoperative Ileus After Elective Colectomy?
The purpose of the investigators study is to investigate the effects of coffee on the return of bowel function and appetite, length of hospital stay, and complications after elective open colectomy in a prospective randomized trial. The primary efficacy endpoint is time to first bowel movement.
|Study Design:||Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Supportive Care
|Official Title:||Does Coffee Intake Reduce Postoperative Ileus After Elective Colectomy?|
- Time to first bowel movement [ Time Frame: patients postoperative in hospital stay (mean 6 days) ] [ Designated as safety issue: No ]Time from end of surgery until patient's first bowel movement (i.e. passage of stool).
|Study Start Date:||March 2010|
|Study Completion Date:||March 2011|
|Primary Completion Date:||March 2011 (Final data collection date for primary outcome measure)|
Active Comparator: Treatment arm: coffee
Other: Postoperative coffee
schedule for coffee administration for the present trial was chosen as follows (starting 6 hours postoperatively):
Other Name: Lavazza Blue Espresso Dolce 100% Arabica coffee
Placebo Comparator: Water arm
The control drink consists of 100 ml warm water
The control drink consists of 100 ml warm water which is administered according a same fixed schedule as Group A starting 6 hours postoperatively:
Other Name: tap water
Coffee is a popular beverage. Its effects on general well being, central nervous system and cardiovascular system are well known, but there is limited information regarding its effects on gastrointestinal function.