Altered Faecal Protease Activity in Irritable Bowel Syndrome Patients in China

This study is enrolling participants by invitation only.
Information provided by:
Xi’an Jiaotong University College of Medicine Identifier:
First received: February 1, 2010
Last updated: NA
Last verified: January 2010
History: No changes posted

Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder haracterised by abdominal pain or discomfort associated with altered bowel habits,while the mechanism is still not understood.Recent advances have conceptualized the faecal supernatants of diarrhoea-predominant IBS have a substantially higher serine protease activity, while in china,almost no studies have reported about protease activity in IBS.

Irritable Bowel Syndrome

Study Type: Observational
Study Design: Observational Model: Case Control

Resource links provided by NLM:

Further study details as provided by Xi’an Jiaotong University College of Medicine:

Estimated Enrollment: 60
Study Start Date: January 2010


Ages Eligible for Study:   18 Years to 70 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population

Outpatients in the second affiliated hospital of xi'an jiaotong university


Inclusion Criteria:

  • Patients fulfilling the Rome III criteria for IBS participated in the study -

Exclusion Criteria:

  • Organic gastrointestinal disorders were excluded by detailed blood and stool analyses, serological assays and colonoscopy.
  Contacts and Locations
No Contacts or Locations Provided
  More Information

No publications provided

Responsible Party: the second affiliated hospital of xi'an jiaotong university Identifier: NCT01060527     History of Changes
Other Study ID Numbers: xi'an JTU091202
Study First Received: February 1, 2010
Last Updated: February 1, 2010
Health Authority: United States: Food and Drug Administration

Keywords provided by Xi’an Jiaotong University College of Medicine:
irritable bowel syndrome,protease activity,China

Additional relevant MeSH terms:
Irritable Bowel Syndrome
Colonic Diseases, Functional
Colonic Diseases
Intestinal Diseases
Gastrointestinal Diseases
Digestive System Diseases processed this record on April 16, 2014