Enhancement and Restoring of Low Dose Abdominal CT Images

The recruitment status of this study is unknown because the information has not been verified recently.

Verified November 2009 by University of Oslo.
Recruitment status was Recruiting

Sponsor:

Collaborator:

Sykehuset Buskerud HF

Information provided by:

University of Oslo

ClinicalTrials.gov Identifier:

NCT01059032

First received: January 21, 2010

Last updated: February 1, 2010

Last verified: November 2009

History of Changes

Purpose

Through the rapid growth of multislice Computer Tomography (CT) imaging, radiation protection has become a major issue in the radiological community. Optimizing CT scanning is a key task when keeping the radiation doses as low as reasonable achievable (the ALARA principle). Post processing filters can improve and restore grainy and noisy low dose CT images by enhancing structure and reducing image noise. In our study of 10 patients, the investigators perform a preliminary evaluation of a novel post processing filter, which does picture element correlations in all three spatial dimensions. By comparing normal dose pictures with unprocessed low-dose pictures and pictures processed with two dimentional (2D) and three dimentional (3D) filters,the investigators will be able to assess the possible clinical value of the 3D filter. This project is collaboration between Buskerud Hospital (BU), Buskerud University College, Norwegian Radiation Protection Authority (NRPA) and Center for Medical Image Science and Visualization (CMIV). The project is part of the PhD of Lars Borgen.

Condition	Intervention	Phase
Radiation Protection	Other: Using a 3 dimentional post processing filter	Phase 1

Study Type:	Interventional
Study Design:	Allocation: Randomized Endpoint Classification: Efficacy Study Intervention Model: Parallel Assignment Masking: Double Blind (Subject, Investigator) Primary Purpose: Diagnostic
Official Title:	Enhancement and Restoring of Low Dose Abdominal CT Images by a Novel Adaptive Nonlinear 3D Post Processing Filter - a Prospective Blinded Interventional Study

Further study details as provided by University of Oslo:

Primary Outcome Measures:

Rating of image quality [ Time Frame: 3-6 months ] [ Designated as safety issue: No ]

Estimated Enrollment:	12
Study Start Date:	December 2009
Estimated Study Completion Date:	December 2011
Estimated Primary Completion Date:	December 2010 (Final data collection date for primary outcome measure)

Arms	Assigned Interventions
No Intervention: Unenhanced images
Enhanced images Enhanced images	Other: Using a 3 dimentional post processing filter Using a 3 dimentional post processing filter

Eligibility

Ages Eligible for Study:	60 Years to 90 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes

Criteria

Inclusion Criteria:

Outpatients, Male or female,Age above 60 years, Referred to our department for an abdominal CT with intravenous contrast.

Exclusion Criteria:

Abdominal diameter less than 80cm or larger than 100cm, Gross pancreatic pathology, Gross anatomic anomalies in the investigated region, Intolerance of intravenous contrast

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT01059032

Contacts

Contact: Lars Borgen, MD

0004795777125

lars.borgen@sb-hf.no

Locations

Norway
Buskerud Hospital	Recruiting
Drammen, Norway, 3014
Contact: Lars Borgen, MD 004795777125 lars.borgen@sb-hf.no
Principal Investigator: Lars Borgen, MD

Sponsors and Collaborators

University of Oslo

Sykehuset Buskerud HF

More Information

No publications provided

Responsible Party:	Frode Lærum, MD, PhD, Akershus University Hospital
ClinicalTrials.gov Identifier:	NCT01059032 History of Changes
Other Study ID Numbers:	15017044793
Study First Received:	January 21, 2010
Last Updated:	February 1, 2010
Health Authority:	Norway: Norwegian Social Science Data Services

ClinicalTrials.gov processed this record on May 21, 2013

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