Expression and Localization of FP Prostaglandin Receptor in Human Ocular Tissues
Recruitment status was Not yet recruiting
to approve the expression of PGF2α receptors in hair follicle in ocular skin tissue, explaining the hypertrichotic effect of PG analogues as intraocular pressure lowering treatment.
Malposition of the Lower Lid
|Study Design:||Observational Model: Case-Only
Time Perspective: Prospective
|Official Title:||Expression and Localization of FP Prostaglandin Receptor in Human Ocular Tissues|
|Study Start Date:||February 2010|
50 hair follicle dissection - human lower lid skin and lashes will be derived from lateral tarsal strip (LTS) dissected routinely in ectropion repair surgery, the skin strip is dissected routinely in this surgery , without any relation to our study. The study will be planned according to Helsinki declaration for Paraffin embedded LTS tissue sections (4 µ) will be processed and examined in immunohistochemistry lab. FP receptor proteins expression, using subtype-specific polyclonal antibodies, will be detected by the light microscopic level, according to manufacturer instruction.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01054157
|Principal Investigator:||halah el naddaf, doctor||Meir Medical Center|