Now Available for Public Comment: Notice of Proposed Rulemaking (NPRM) for FDAAA 801 and NIH Draft Reporting Policy for NIH-Funded Trials

Frequency of Aerobic/Resistance Training in Older Women (SWEET)

This study has been completed.
Sponsor:
Collaborator:
Information provided by (Responsible Party):
Gary Hunter, PhD, University of Alabama at Birmingham
ClinicalTrials.gov Identifier:
NCT01031394
First received: December 10, 2009
Last updated: April 23, 2012
Last verified: April 2012
  Purpose

The objective of this study is to provide insight into the effects combined training frequency has on improving fitness, ease of physical activity, and maintenance of a high total energy expenditure. Such information is critical to our understanding of ways to improve well-being, quality of life, and independence of an aging population. 105 participants will be enrolled in this study. The length of time for your involvement in the study will be 32 weeks. You will undergo the procedures listed in this consent form on 3 separate occasions-initially at your entry, at 16 weeks and again at 32 weeks.


Condition Intervention
Aging
Other: Frequency of Aerobic/Resistance Training - 3 to 3

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single Blind (Subject)
Primary Purpose: Treatment
Official Title: Frequency of Aerobic/Resistance Training in Older Women

Further study details as provided by University of Alabama at Birmingham:

Primary Outcome Measures:
  • Use a repeated measures analysis to compare differences in TEE and other parameters among the 3 intervention groups across time [ Time Frame: over 32 weeks of training ] [ Designated as safety issue: No ]

Estimated Enrollment: 105
Study Start Date: January 2004
Study Completion Date: March 2011
Primary Completion Date: March 2011 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Active Comparator: Group 1
1 aerobic and 1 resistance training per week
Other: Frequency of Aerobic/Resistance Training - 3 to 3
comparing group results based upon frequency of exercise
Other Name: freqency of aerobic and resistance training
Active Comparator: Group 2
2 aerobic and 2 resistance training each per week
Other: Frequency of Aerobic/Resistance Training - 3 to 3
comparing group results based upon frequency of exercise
Other Name: freqency of aerobic and resistance training
Active Comparator: Group 3
3 aerobic and 3 resistance training per week
Other: Frequency of Aerobic/Resistance Training - 3 to 3
comparing group results based upon frequency of exercise
Other Name: freqency of aerobic and resistance training

Detailed Description:

Frequency of aerobic/resistance training in older women

Abstract Combined aerobic and resistance training have unique benefits for maintaining a physical activity (PA). However, the optimal training program for combining these two modes of training in older adults is unknown. This study builds on current and past studies showing that training induced gains in aerobic fitness, muscle strength, and ease of PA are important for maintaining an active lifestyle, a favorable body composition, and high bone density. Traditionally 3 d/wk combined training has been felt to be optimal while recent studies suggest 1 d/wk combined training may create similar adaptations as more frequent training. However, our previous and ongoing studies suggest that 1 d/wk combined aerobic and resistance training (C1) may be insufficient stimulus to induce optimal adaptations and that 3 d/wk combined training (C3) may be too frequent a stimulus for older adults. This study will enable us to compare the effects of C1, 2 d/wk combined training (C2), and C3 on fitness, body composition, ease of PA, PA, and total free-living energy expenditure (TEE). We hypothesize that C2 will result in a larger increase in muscle size, bone density, strength, aerobic capacity, power, ease of PA, PA, and TEE than either C1 or C3. Circulating cytokines and psychological mood states linked to chronic overstress will also be examined. Objectives: We will examine changes in circulating cytokines, mood states, muscle size, bone density, aerobic capacity, strength, power, ease of PA, PA, and TEE following 16 and 32 wks training. Design: We will to evaluate 78 (>60 yrs) Black and White women matched for age, race, and BMI into C1, C2, or C3 groups prior to, after 16, and after 32 wks training. Women will undergo evaluation of metabolic parameters in a General Clinical Research Center. Significance: This study should provide insight into the effects combined training frequency has on improving fitness, ease of PA, and maintenance of a high TEE. Such information is critical to our understanding of ways to improve well being, quality of life, and independence of an aging population.

  Eligibility

Ages Eligible for Study:   60 Years and older
Genders Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:,

  • healthy women over 60 years of age,
  • Caucasian or African-American.

Exclusion Criteria:

  • smoking,
  • diabetes,
  • osteoporosis,
  • inability to coperform weight bearing exercises, currently performing to much exercise.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01031394

Locations
United States, Alabama
UAB
Birmingham, Alabama, United States, 35294
Sponsors and Collaborators
University of Alabama at Birmingham
  More Information

No publications provided

Responsible Party: Gary Hunter, PhD, Professor, UAB School of Education, University of Alabama at Birmingham
ClinicalTrials.gov Identifier: NCT01031394     History of Changes
Other Study ID Numbers: F050820002, R01AG027084
Study First Received: December 10, 2009
Last Updated: April 23, 2012
Health Authority: United States: Institutional Review Board

Keywords provided by University of Alabama at Birmingham:
exercise
resistance training

ClinicalTrials.gov processed this record on November 24, 2014