Effects of Sleep Duration on Eating and Activity Behaviors
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Purpose
The purpose of the proposed study is to determine whether the amount children sleep is associated with changes in hormones, hunger, motivation to eat, and food intake. Fifty children 8-11 years old who sleep 9-10 hours per night will be enrolled for a 3-week study. For 1 week each, children will be asked to sleep their typical amount, increase their sleep by 1-½ hours, and decrease their sleep by 1-½ hours. Half of the children will be asked to increase their sleep first and half to decrease their sleep first. During each week, the following will be gathered: sleep duration (measured by actigraphy, which is a small device that measures sleep), levels of hormones measured through blood draws, self-reported hunger and appetite, food intake (measured by 3 days of 24-hour recall), how motivated children are to eat (measured using a computer activity), and child height and weight. We believe that when children sleep less they will show changes in hormones associated with hunger and appetite, report being hungrier, be more motivated to eat, and eat more food.
| Condition | Intervention |
|---|---|
|
Sleep Obesity |
Behavioral: Increase Sleep Behavioral: Decrease Sleep |
| Study Type: | Observational |
| Study Design: | Observational Model: Case-Only Time Perspective: Prospective |
| Official Title: | Sleep Duration and Pediatric Overweight: the Role of Eating Behaviors |
- absolute reinforcing value of food as compared to sedentary activities [ Time Frame: after 1 week of typical sleep duration, after 1 week of decreased sleep duration, after 1 week of increased sleep duration ] [ Designated as safety issue: No ]
- plasma levels of leptin and ghrelin [ Time Frame: after 1 week of typical sleep duration, after 1 week of decreased sleep duration, after 1 week of increased sleep duration ] [ Designated as safety issue: No ]
- caloric intake [ Time Frame: after 1 week of typical sleep duration, after 1 week of decreased sleep duration, after 1 week of increased sleep duration ] [ Designated as safety issue: No ]
- levels of physical activity [ Time Frame: after 1 week of typical sleep duration, after 1 week of decreased sleep duration, after 1 week of increased sleep duration ] [ Designated as safety issue: No ]
- subjective ratings of hunger and appetite [ Time Frame: after 1 week of typical sleep duration, after 1 week of decreased sleep duration, after 1 week of increased sleep duration ] [ Designated as safety issue: No ]
Biospecimen Retention: Samples Without DNA
2 ml of whole blood drawn at each of 3 assessments
| Enrollment: | 37 |
| Study Start Date: | February 2009 |
| Study Completion Date: | January 2012 |
| Primary Completion Date: | January 2012 (Final data collection date for primary outcome measure) |
| Groups/Cohorts | Assigned Interventions |
|---|---|
|
Children with Insufficient Sleep
Children who sleep approximately 9-10 hours/night
|
Behavioral: Increase Sleep
Children are asked to increase their sleep by approximately 1 1/2 hours/night for 1 week.
Behavioral: Decrease Sleep
Children are asked to decrease their sleep by approximately 1 1/2 hours/night.
|
Eligibility| Ages Eligible for Study: | 8 Years to 11 Years |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | Yes |
| Sampling Method: | Non-Probability Sample |
Children ages 8-11 years old recruited from Southeastern New England.
Inclusion Criteria:
- Age 8-11 years old
- BMI for age and gender > 5th percentile (but no greater than 100% overweight)
- Sleep approximately 9-10 hours nightly
- Attend elementary school
- Like at least 1 food and 1 activity used in the reinforcement paradigm
- Able to understand and complete the reinforcement paradigm
Exclusion Criteria:
- Existence of a diagnosable sleep disorder
- Medical or psychiatric condition that could influence sleep or weight
- Onset of menarche
- Inability to complete study materials, including diagnosed disabilities
- Dietary restrictions/allergies to foods used in the study that preclude them from study participation
Contacts and Locations| United States, Rhode Island | |
| Weight Control and Diabetes Research Center | |
| Providence, Rhode Island, United States, 02903 | |
| Principal Investigator: | Chantelle N Hart, PhD | The Miriam Hospital/Alpert Medical School of Brown University |
More Information
Additional Information:
No publications provided
| Responsible Party: | The Miriam Hospital |
| ClinicalTrials.gov Identifier: | NCT01030107 History of Changes |
| Other Study ID Numbers: | 1-08-JF-17 |
| Study First Received: | December 9, 2009 |
| Last Updated: | October 4, 2012 |
| Health Authority: | United States: Institutional Review Board |
Keywords provided by The Miriam Hospital:
|
sleep obesity children eating behaviors |
activity leptin ghrelin |
Additional relevant MeSH terms:
|
Obesity Overnutrition Nutrition Disorders |
Overweight Body Weight Signs and Symptoms |
ClinicalTrials.gov processed this record on May 21, 2013