Will Listening to Music Make it Easier to Take a Visual Field Test?

This study has been completed.
Sponsor:
Information provided by:
Wills Eye
ClinicalTrials.gov Identifier:
NCT01027039
First received: December 4, 2009
Last updated: June 24, 2010
Last verified: June 2010
  Purpose

The purpose of this study is to examine if there is a difference between glaucoma patients having background music and not having background music before visual field testing.


Condition
Glaucoma

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: The Effect of Mozart Music on Visual Field Testing in Glaucoma Patients: Will Music Tame the Savage Perimeter?

Resource links provided by NLM:


Further study details as provided by Wills Eye:

Enrollment: 160
Study Start Date: June 2008
Study Completion Date: September 2009
Primary Completion Date: September 2009 (Final data collection date for primary outcome measure)
Groups/Cohorts
Patients using noise-reducing headphones
Patients using no headphones
Patients using headphones with music playing

Detailed Description:

Glaucoma is one of the leading causes of blindness in the United States. Over 2.5 million people in the United States have glaucoma. The goal of ophthalmologists is two-fold: 1) to detect glaucoma early, and 2) to stop the progression of disease and subsequent visual loss.

Many parameters are used to detect and follow glaucoma over the patient's lifetime including optic nerve appearance, intraocular pressure by applanation and visual field perimetry testing results. Perimetry testing aims to detect visual field loss that may be associated with glaucoma and institute more aggressive treatment measures when necessary. However, it is suspected that 50% or more of the optic nerve fibers are already irreversibly damaged before a visual field defect can be identified on testing. Furthermore, the patient's ability to take a visual field test is paramount in the doctor's ability to interpret the test. That is, if a visual field test taker performs the test with low reliability (i.e. too many false positive, false negative or fixation losses), the interpretability of the test by the ophthalmologist is difficult or impossible.

Interestingly, a recent study in the British Journal of Ophthalmology1 suggested the positive effect Mozart music has on visual field test taking ability. This study showed better first time automated perimetry performance in normals immediately following exposure to the first 10 minutes of Mozart's Sonata for Two Pianos in D Major. The music group had 20 times fewer fixation losses, three times fewer false positive responses and 10 times fewer false negative responses.

No study has determined if Mozart music improves the reliability indices of Humphrey visual field testing for glaucoma patients or experienced test takers. In efforts to improve patient's reliability on visual field testing, we propose a randomized controlled trial to determine if listening to music before field testing improves testing reliability.

  Eligibility

Ages Eligible for Study:   40 Years to 80 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population

glaucoma service

Criteria

Inclusion Criteria:

  • Age range: 40-80 years
  • Best corrected visual acuity: 20/50 or better in both eyes
  • Experienced visual field test takers only: Patient has taken at least 2 prior visual field tests
  • Mean defect values: MD no greater than 15
  • Reliability on prior visual field indices must each be less than or equal to 40%
  • Glaucoma type: Open angle glaucoma (including primary open angle glaucoma, pigmentary glaucoma and exfoliative glaucoma) angle closure glaucoma and low tension glaucoma
  • Visual field testing program: Humphrey 24-2 Sita Standard
  • Number of eyes per patient: Both (2) eyes will be tested for each subject

Exclusion Criteria:

  • Patients with other ocular disease affecting central vision other than mild- moderate nuclear sclerosis (i.e. patients with macular scar, age-related macular degeneration, diabetic retinopathy, etc.)
  • Systemic conditions affecting ability to take HVF (i.e. dementia, CVA, severe arthritis, etc.)
  • Any visual field taken that is not the Humphrey 24-2 SITA Standard field will not be acceptable
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01027039

Locations
United States, Pennsylvania
Wills Eye Glaucoma Service
Philadelphia, Pennsylvania, United States, 19107
Sponsors and Collaborators
Wills Eye
  More Information

No publications provided by Wills Eye

Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: Jonathan Myers MD, Wills Eye Glaucoma Service
ClinicalTrials.gov Identifier: NCT01027039     History of Changes
Other Study ID Numbers: 07-829E
Study First Received: December 4, 2009
Last Updated: June 24, 2010
Health Authority: United States: Institutional Review Board

Keywords provided by Wills Eye:
primary open angle glaucoma
pigmentary glaucoma
exfoliative glaucoma
angle closure glaucoma
low tension glaucoma

Additional relevant MeSH terms:
Glaucoma
Ocular Hypertension
Eye Diseases

ClinicalTrials.gov processed this record on October 01, 2014