Trial record 1 of 1 for:    "Auditory neuropathy"
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Auditory Neuropathy and Cochlear Implants

This study has been completed.
Sponsor:
Collaborator:
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.
Information provided by:
University of Sao Paulo
ClinicalTrials.gov Identifier:
NCT01023932
First received: December 1, 2009
Last updated: NA
Last verified: December 2009
History: No changes posted
  Purpose

The electrical stimulation generated by the Cochlear Implant (CI) may improve the neural synchrony and hence contribute to the development of auditory skills in patients with Auditory Neuropathy / Auditory Dys-synchrony (AN/AD). Goal: The goal of the research was to evaluate the auditory performance and the characteristics of the electrically evoked compound action potential (ECAP) in a group of 18 cochlear implants recipients with AN/AD.The auditory perception was evaluated by sound field thresholds and speech perception tests. To evaluate ECAP's characteristics, the threshold and amplitude of neural response together with the amplitude growth and recovery functions were evaluated at 80Hz stimulation rate.The CI was seen as an efficient resource to develop auditory skills in 94% of the AN/AD patients considered by the research. The auditory perception benefits as well as the possibility to measure the ECAP showed that the electrical stimulation could compensate the neural dys-synchrony caused by the AN/AD. However, a unique clinical procedure cannot be proposed at this point. Therefore, a careful and complete evaluation of each AN/AD patient before recommending the Cochlear Implant is advised


Condition Intervention
Cochlear Implants
Auditory Neuropathy
Device: Cochlear Implants

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Cochlear Implants in Children With Auditory Neuropathy/ Auditory Dys-Synchrony

Resource links provided by NLM:


Further study details as provided by University of Sao Paulo:

Primary Outcome Measures:
  • The CI was seen as an efficient resource to develop auditory skills in 94% of the AN/AD patients considered by the research.

Study Start Date: September 2006
Estimated Study Completion Date: September 2009
Groups/Cohorts Assigned Interventions
Auditory Neuropathy Patients Device: Cochlear Implants

  Eligibility

Ages Eligible for Study:   2 Years and older
Genders Eligible for Study:   Both
Sampling Method:   Non-Probability Sample
Study Population

Children with auditory neuropathy who had received a cochlear implant

Criteria

Inclusion Criteria:

  • All children with AN/AD who had received the cochlear implant during the research´s period.
  Contacts and Locations
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Please refer to this study by its ClinicalTrials.gov identifier: NCT01023932

Locations
Brazil
Bionic Ear Center
Sao Paulo, SP, Brazil, 1150000
Sponsors and Collaborators
University of Sao Paulo
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.
  More Information

No publications provided by University of Sao Paulo

Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: Ana Claudia Martinho de Carvalho
ClinicalTrials.gov Identifier: NCT01023932     History of Changes
Other Study ID Numbers: NADA2009
Study First Received: December 1, 2009
Last Updated: December 1, 2009
Health Authority: Brazil: Ethics Committee

Additional relevant MeSH terms:
Demyelinating Diseases
Polyneuropathies
Nerve Compression Syndromes
Neurologic Manifestations
Neurotoxicity Syndromes
Hearing Loss, Central
Nervous System Diseases
Peripheral Nervous System Diseases
Neuromuscular Diseases
Signs and Symptoms
Poisoning
Substance-Related Disorders
Hearing Loss, Sensorineural
Hearing Loss
Hearing Disorders
Ear Diseases
Otorhinolaryngologic Diseases
Auditory Diseases, Central
Retrocochlear Diseases
Brain Diseases
Central Nervous System Diseases
Sensation Disorders

ClinicalTrials.gov processed this record on July 20, 2014