Correlation Between Various Inflammatory Markers and Vascular Inflammation Measured by 18FDG-PET
Vascular inflammation is a key factor in both the pathogenesis and outcome of atherosclerosis. Various inflammatory markers such as LpPLA2,MCP-2 and hsCRP are well-known prognostic factors for the cardiovascular event.
18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) is a promising tool for identifying and quantifying vascular inflammation within atherosclerotic plaques.Therefore, the purpose of the study is to demonstrate the correlation between various inflammatory markers and vascular inflammation detected by 18FDG-PET.
|Study Design:||Observational Model: Cohort
Time Perspective: Cross-Sectional
|Official Title:||Correlation of Inflammatory Markers Such as LpPLA2,MCP-1 and hsCRP for Predicting Vascular Inflammation; Analysis With 18F-Fluorodeoxyglucose Positron Emission Tomography|
- Correlation between various inflammatory markers including LpPLA2,MCP-1 and hsCRP and vascular inflammation analyzed by 18FDG-PET [ Time Frame: 12 weeks ] [ Designated as safety issue: No ]
- Correlation between various inflammatory markers and atherosclerosis measured by carotid intima media thickness [ Time Frame: 12 weeks ] [ Designated as safety issue: No ]
Biospecimen Retention: Samples Without DNA
Whole blood, serum
|Study Start Date:||December 2009|
|Study Completion Date:||January 2010|
|Primary Completion Date:||January 2010 (Final data collection date for primary outcome measure)|
Other: Cross section study
This is not intervention study. The purpose of the study is to examine the relationship between various inflammatory markers and PET imaging at the cross section setting