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Apathy in Parkinson Disease: Clinical, Physiopathological and Pharmacological Study

The recruitment status of this study is unknown because the information has not been verified recently.
Verified November 2009 by University Hospital, Grenoble.
Recruitment status was  Recruiting
Sponsor:
Collaborator:
Institut National de la Santé Et de la Recherche Médicale, France
Information provided by:
University Hospital, Grenoble
ClinicalTrials.gov Identifier:
NCT01020682
First received: November 24, 2009
Last updated: NA
Last verified: November 2009
History: No changes posted
  Purpose

Apathy has been reported to occur after subthalamic nucleus stimulation (STN-DBS), a treatment of motor complications in advanced Parkinson's disease (PD). It is not known whether postoperative apathy is related to dopamine withdrawal or a side effect of STN DBS. The researchers investigated potential predictors of apathy, and the effect of dopamine agonist treatment.


Condition
Apathy in Parkinson Disease

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Apathy in Parkinson Disease: Clinical, Physiopathological and Pharmacological Study

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by University Hospital, Grenoble:

Estimated Enrollment: 120
Study Start Date: January 2005
Estimated Study Completion Date: June 2011
Primary Completion Date: February 2006 (Final data collection date for primary outcome measure)
  Eligibility

Ages Eligible for Study:   18 Years to 70 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population

Parkinson's disease

Criteria

Inclusion Criteria:

  • Parkinson disease

Exclusion Criteria:

  • Mattis scale < 130
  • Beck scale > 20
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01020682

Contacts
Contact: Krack Paul, MD 0476765791 paul.krack@ujf-grenoble.fr

Locations
France
Hopital neurologique Recruiting
Lyon, France, 69000
Contact: Broussolle , MD            
Sponsors and Collaborators
University Hospital, Grenoble
Institut National de la Santé Et de la Recherche Médicale, France
  More Information

No publications provided

Responsible Party: Délégation à la recherche clinique, CHU de grenoble
ClinicalTrials.gov Identifier: NCT01020682     History of Changes
Other Study ID Numbers: APATHIE
Study First Received: November 24, 2009
Last Updated: November 24, 2009
Health Authority: France: Afssaps - Agence française de sécurité sanitaire des produits de santé (Saint-Denis)

Keywords provided by University Hospital, Grenoble:
apathy
parkinson
agonist dopaminergic

Additional relevant MeSH terms:
Parkinson Disease
Parkinsonian Disorders
Basal Ganglia Diseases
Brain Diseases
 Central Nervous System Diseases
Nervous System Diseases
Movement Disorders
Neurodegenerative Diseases

ClinicalTrials.gov processed this record on May 21, 2013