Now Available for Public Comment: Notice of Proposed Rulemaking (NPRM) for FDAAA 801 and NIH Draft Reporting Policy for NIH-Funded Trials

Compare the Therapeutic Effect Treated With Tamsulosin and Progesterone After ESWL( Extra Corporeal Shock Wave Lithotripsy) in Urinary Calculus

The recruitment status of this study is unknown because the information has not been verified recently.
Verified November 2009 by Chongqing Medical University.
Recruitment status was  Recruiting
Sponsor:
Information provided by:
Chongqing Medical University
ClinicalTrials.gov Identifier:
NCT01010048
First received: November 6, 2009
Last updated: November 12, 2009
Last verified: November 2009
  Purpose

The purpose of this study is to compare the stone clearance rate treated with different drugs after ESWL in urinary calculus,These drugs are often used in urinary calculus,such as progesterone,tamsulosin,propantheline Bromide and nifedipine.In these study the investigators want to investigate different effect of these drugs use to treat urinary calculus after ESWL.


Condition Intervention Phase
Urinary Calculus
Drug: progesterone,tamsulosin,propantheline Bromide and nifedipine
Phase 4

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Bio-equivalence Study
Intervention Model: Parallel Assignment
Masking: Single Blind (Outcomes Assessor)
Primary Purpose: Treatment
Official Title: the Therapeutic Effect Treated With Tamsulosin After ESWL in Urinary Calculus

Resource links provided by NLM:


Further study details as provided by Chongqing Medical University:

Primary Outcome Measures:
  • different effect of these drugs use to treat urinary calculus after ESWL [ Time Frame: 2weeks ] [ Designated as safety issue: Yes ]

Estimated Enrollment: 120
Study Start Date: October 2009
Estimated Study Completion Date: December 2010
Estimated Primary Completion Date: October 2009 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: progesterone,tamsulosin,propantheline Bromide and nifedipine
different effect of these drugs use to treat urinary calculus after ESWL
Drug: progesterone,tamsulosin,propantheline Bromide and nifedipine
clearance rate of stone

Detailed Description:

There is 4 groups in these investigation, group1 urinary calculus treated with ESWL only ,group2 urinary calculus treated with ESWL and tamsulosin,group3 urinary calculus treated with ESWL and progesterone,group4 urinary calculus treated with ESWL ,propantheline Bromide and nifedipine.We want to investigate which one is better or not in urinary calculus treated with ESWL .

  Eligibility

Ages Eligible for Study:   18 Years to 68 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • From 18 years old to 68 years old,
  • urinary calculus could be treated by ESWL,
  • the calculus size is from 4-25mm

Exclusion Criteria:

  • Less than 18 years old or more than 68 years old,
  • the calculus size is from Less than4 or larger than 25mm
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01010048

Contacts
Contact: Yunfeng He, Doctor 86-23-89011121
Contact: Xiaohou Wu, Doctor 86-23-89011122

Locations
China, Chongqing
The First Affiliated Hospital, ChongQing medical University Recruiting
ChongQing, Chongqing, China, 400016
Contact: Yunfeng He, Doctor    86-23-89011121      
Contact: Xiaohou Wu, Doctor    86-23-89011122      
Sponsors and Collaborators
Chongqing Medical University
Investigators
Study Chair: xiaohou wu, doctor First Affiliated Hospital of Chongqing Medical University
  More Information

No publications provided

Responsible Party: He Yunfeng, The First Affiliated Hospital ,Chongqing Medical University
ClinicalTrials.gov Identifier: NCT01010048     History of Changes
Other Study ID Numbers: CQMU
Study First Received: November 6, 2009
Last Updated: November 12, 2009
Health Authority: China: Food and Drug Administration

Keywords provided by Chongqing Medical University:
ESWL
urinary calculus
drugs treat

Additional relevant MeSH terms:
Calculi
Urinary Calculi
Pathological Conditions, Anatomical
Urolithiasis
Urologic Diseases
Nifedipine
Progesterone
Propantheline
Tamsulosin
Adrenergic Agents
Adrenergic Antagonists
Adrenergic alpha-1 Receptor Antagonists
Adrenergic alpha-Antagonists
Anti-Ulcer Agents
Calcium Channel Blockers
Cardiovascular Agents
Cholinergic Agents
Cholinergic Antagonists
Gastrointestinal Agents
Hormones
Hormones, Hormone Substitutes, and Hormone Antagonists
Membrane Transport Modulators
Molecular Mechanisms of Pharmacological Action
Muscarinic Antagonists
Neurotransmitter Agents
Pharmacologic Actions
Physiological Effects of Drugs
Progestins
Reproductive Control Agents
Therapeutic Uses

ClinicalTrials.gov processed this record on November 20, 2014