The Migraine and Pain Study GeneBank at Scripps Clinic Registry (MAPS)
The objective of this study is to obtain blood or saliva samples to define genes for migraine and pain diseases.
|Study Design:||Observational Model: Family-Based|
|Official Title:||The Migraine and Pain Study GeneBank at Scripps Clinic Registry (MAPS)|
- Gene identification [ Time Frame: end of study ] [ Designated as safety issue: No ]By creating a MAPS GeneBank from these patients' blood/saliva donations we will ultimately be able to define genes for migraine and pain diseases.
Biospecimen Retention: Samples With DNA
Approximately 20 milliliters of blood will be dispensed as follows: 2 X 8.5 ml PAX DNA Tubes OR 2 mLs of Saliva may be collected from each patient in a provided container. Saliva will only be collected on those individuals who do not wish to undergo phlebotomy for blood collection.
|Study Start Date:||January 2009|
|Estimated Primary Completion Date:||September 2014 (Final data collection date for primary outcome measure)|
Patients 10 to 18 years of age with the diagnosis of Migraine disease and at least one of their biologic parents will be included in this study.
It is estimated that over one-third of the world's population suffers from persistent or recurrent pain. Migraine is highly heritable and the majority of juveniles who suffer from the disorder have a mother or father who also have the disease. The blood or saliva samples will go through DNA analysis and be sequenced for candidate genes or subjected to whole-genome sequencing. By creating a MAPS GeneBank from these patients' blood/saliva donations we will ultimately be able to define genes for migraine and pain diseases.
|United States, California|
|La Jolla, California, United States, 92037|
|Principal Investigator:||Christy M Jackson, M.D.||Scrippshealth|