Evaluation of Radiesse® Dermal Filler for Hand Rejuvenation

Inclusion Criteria

• Has right and left hands with a rating of 3 or 4 on the BHVSS as determined by the treating physician
• Is at least 18 years of age
• Signs a written informed consent
• Understands and accepts the obligation not to receive any other procedures in the dorsum of the hands through 12 month follow up
• Understands and accepts the obligation and is logistically able to present for all scheduled follow-up visits

Exclusion Criteria

• Has planned activities during study that could interfere with treatment (i.e., boxing) or that impose significant force to the hands.
• Has history of hypertropic scarring.
• Has a known bleeding disorder (e.g., thrombocytopenia, thrombasthenia, or von Willebrand's disease).
• Has received or is anticipated to receive antiplatelets, anticoagulants, thrombolytics , vitamin E or anti-inflammatories within 2 weeks pre treatment.
• Is receiving systemic corticosteroids or anabolic steroids (standard doses of inhaled or nasal corticosteroids are acceptable).
• Has a history of chronic or recurrent infection (e.g., Pseudomona paronychia) or inflammation (e.g., rheumatoid arthritis) that would preclude participation in the study.
• Has a known hypersensitivity to any of the components of Radiesse or local anesthesia.
• Has received the following in the dorsum of the hand within 4 weeks of treatment or intends to receive these products and or treatments during the study: Over the-counter wrinkle products (e.g., alpha-hydroxy acids) or prescription treatments (e.g., Renova, Retin-A, micro-dermabrasion, chemical peels)
• Has had any dermal fillers or surgery in the dorsum of the hand.
• Is a female of child bearing potential and not using medically effective birth control or is pregnant or lactating.