Incidence of Phantom Limb Pain and Method of Anesthesia After Lower Extremity Amputation
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Purpose
Phantom limb pain (pain originating from where an amputated limb once was) is a common occurrence after lower extremity amputations, with some sources noting incidence to be as high as 60-80% six months after surgery. This pain can eventually subside, however, cases have been reported of incidence 10 years after surgery. This pain is not only physically detrimental, but can also be psychologically detrimental after a difficult to accept change in the body. Prior studies have been performed using regional anesthetic techniques (including spinals and epidurals) and different medications to attempt to reduce the incidence of phantom limb pain, however, the data have been mostly inconclusive. Of interest, prior studies have not addressed peripheral nerve blocks, a method of anesthesia/analgesia more commonly employed for amputations recently. The purpose of our retrospective study is to look at the incidence of phantom limb pain at our institution over a two year period to determine if peripheral nerve blocks result in a significantly reduced incidence compared to other techniques (spinal, epidural, general anesthesia only). In addition, there is little data on relation of reason for amputation and presence of preoperative neuropathy and incidence of phantom pain. As secondary endpoints, the investigators wish to investigate if certain reasons for amputation (trauma, peripheral vascular disease, diabetes, and others) and/or neuropathy lead to a higher incidence of phantom limb pain. The results of this study could impact future management of patients who are to receive amputations and may lead to further prospective studies on the topics involved.
| Condition | Intervention |
|---|---|
|
Phantom Limb Pain |
Procedure: Lower extremity amputation |
| Study Type: | Observational |
| Study Design: | Observational Model: Case-Only Time Perspective: Retrospective |
| Official Title: | Incidence of Phantom Limb Pain and Method of Anesthesia After Lower Extremity Amputation |
| Groups/Cohorts | Assigned Interventions |
|---|---|
| General Anesthesia only | Procedure: Lower extremity amputation |
| Peripheral nerve block | Procedure: Lower extremity amputation |
| spinal | Procedure: Lower extremity amputation |
Eligibility| Ages Eligible for Study: | 18 Years and older |
| Genders Eligible for Study: | Both |
| Sampling Method: | Non-Probability Sample |
Patients who receive lower extremity amputation
Inclusion Criteria:
- Patients who receive lower extremity amputation
Exclusion Criteria:
- Death or incapacitating medical condition since surgery
Contacts and Locations
More Information
No publications provided
| Responsible Party: | Chandramouli Iyer, MD, Veterans Affairs North Texas Health Care System |
| ClinicalTrials.gov Identifier: | NCT01003704 History of Changes |
| Other Study ID Numbers: | 09-059 |
| Study First Received: | October 28, 2009 |
| Last Updated: | October 28, 2009 |
| Health Authority: | United States: Federal Government United States: Institutional Review Board |
Additional relevant MeSH terms:
|
Phantom Limb Perceptual Disorders Neurobehavioral Manifestations Neurologic Manifestations Nervous System Diseases Signs and Symptoms |
Anesthetics Central Nervous System Depressants Physiological Effects of Drugs Pharmacologic Actions Central Nervous System Agents Therapeutic Uses |
ClinicalTrials.gov processed this record on May 19, 2013