SCOT Registry: Small Cell Lung Cancer Treatment and Outcome

This study is ongoing, but not recruiting participants.
Sponsor:
Information provided by (Responsible Party):
GlaxoSmithKline
ClinicalTrials.gov Identifier:
NCT00997061
First received: October 15, 2009
Last updated: March 21, 2013
Last verified: March 2013
  Purpose

The registry is an international, multicenter, observational registry of newly diagnosed patients with SCLC.

Data will be entered into an electronic CRF (eCRF) via Internet access. Treatment plan remains the responsibility of the patient's physician and data collected in this registry will reflect a "real world" approach of the diagnosis and treatment of patients with SCLC.

Approximately 60 centres in 13 countries will take part in this registry. It is expected that about 500 patients will be recruited during a period of 6 to 9 months according to the feasibility.


Condition Intervention
Lung Cancer, Small Cell
Drug: HYCAMTIN

Study Type: Observational
Study Design: Time Perspective: Prospective
Official Title: SCOT Registry: Small Cell Lung Cancer Treatment and Outcome

Resource links provided by NLM:


Further study details as provided by GlaxoSmithKline:

Primary Outcome Measures:
  • Registry with disease, treatment and outcome data collected. [ Time Frame: 6-9mth recruitment period, 18mth study duration. ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • survival rates [ Time Frame: 18 month period ] [ Designated as safety issue: No ]

Estimated Enrollment: 500
Study Start Date: November 2009
Estimated Study Completion Date: March 2013
Primary Completion Date: February 2012 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
HYCAMTIN Drug: HYCAMTIN
Observing patients on HYCAMTIN and other drugs for SCLC.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population

Newly Diagnosed SCLC patients

Criteria

Inclusion Criteria:

  • Male or Female >/= 18 years
  • Diagnosis of small cell lung cancer
  • Patient newly diagnosed with SCLC
  • Has given written informed consent (if applicable)

Exclusion Criteria:

  • Concurrent history of other neoplasm, except curatively treated basal cell skin cancer or adequately treated in-situ carcinoma of the cervix.
  • Patient presenting with recurrence of SCLC.
  • Patients who has received any chemotherapy for the SCLC.
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00997061

Locations
Czech Republic
GSK Investigational Site
Brno, Czech Republic, 625 00
GSK Investigational Site
Plzen, Czech Republic, 305 99
Estonia
GSK Investigational Site
Tallinn, Estonia, 11619
France
GSK Investigational Site
Besançon, France, 25030
GSK Investigational Site
Caen, France, 14033
GSK Investigational Site
Créteil, France, 94010
GSK Investigational Site
Draguignan cedex, France, 83300
GSK Investigational Site
Lorient cedex, France, 56322
GSK Investigational Site
Paris, France, 75020
GSK Investigational Site
Perpignan, France, 66000
GSK Investigational Site
Pessac cedex, France, 33604
GSK Investigational Site
Pierre Benite, France, 69495
GSK Investigational Site
Saint-Priest en Jarez, France, 42271
GSK Investigational Site
Strasbourg, France, 67091
Hungary
GSK Investigational Site
Székesfehérvár, Hungary, 8000
Korea, Republic of
GSK Investigational Site
Seongnam-si, Gyeonggi-do, Korea, Republic of, 463-707
GSK Investigational Site
Seoul, Korea, Republic of, 137-701
GSK Investigational Site
Suwon, Gyeonggi-do, Korea, Republic of, 442-723
Netherlands
GSK Investigational Site
Eindhoven, Netherlands, 5623 EJ
Poland
GSK Investigational Site
Glucholazy, Poland, 41-340
GSK Investigational Site
Lodz, Poland, 93-509
GSK Investigational Site
Lublin, Poland, 20-954
Slovenia
GSK Investigational Site
Golnik, Slovenia, 4204
GSK Investigational Site
Ljubljana, Slovenia, 1000
Spain
GSK Investigational Site
Cordoba, Spain, 14004
GSK Investigational Site
Madrid, Spain, 28034
GSK Investigational Site
Madrid, Spain, 28040
GSK Investigational Site
Palma de Mallorca, Spain, 07014
GSK Investigational Site
Zaragoza, Spain, 50009
Sponsors and Collaborators
GlaxoSmithKline
Investigators
Study Director: GSK Clinical Trials GlaxoSmithKline
  More Information

No publications provided

Responsible Party: GlaxoSmithKline
ClinicalTrials.gov Identifier: NCT00997061     History of Changes
Other Study ID Numbers: 112791
Study First Received: October 15, 2009
Last Updated: March 21, 2013
Health Authority: Czech Republic: Státní ústav pro kontrolu léčiv, Oddělení klinického hodnocení
Spain: Agencia Española del Medicamento y Productos Sanitarios
France: Conseil National de l'Ordre des Médecins
Austria: Agency for Health and Food Safety
Neherlands: Dutch Medical Research in Human Subjects Act (WMO).
Italy: Isituto Superiore di Sanita'
Poland: Centralna Ewidencja Badań Klinicznych Urząd Rejestracji Produktów Leczniczych, Wyrobów Medycznych i Produktów Biobójczych
Germany: Federal Institute for Drugs and Medical Devices
South Korea: Food and Drug Administration

Additional relevant MeSH terms:
Lung Neoplasms
Small Cell Lung Carcinoma
Respiratory Tract Neoplasms
Thoracic Neoplasms
Neoplasms by Site
Neoplasms
Lung Diseases
Respiratory Tract Diseases
Carcinoma, Bronchogenic
Bronchial Neoplasms
Topotecan
Topoisomerase I Inhibitors
Topoisomerase Inhibitors
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action
Pharmacologic Actions
Antineoplastic Agents
Therapeutic Uses

ClinicalTrials.gov processed this record on May 23, 2013