Acute and Longlasting Side Effects Caused by Radiotherapy in the Head and Neck Area
The purpose of this clinical investigation is to evaluate acute and longlasting side effects in patients undergoing radiotherapy for cancer treatment in the head and neck area.
Head and Neck Cancer
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Acute and Longlasting Side Effects Caused by Radiotherapy in the Head and Neck Area|
- salivary flow [ Time Frame: 3 months ] [ Designated as safety issue: No ]
- salivary flow [ Time Frame: 12 months ] [ Designated as safety issue: No ]
|Study Start Date:||January 2008|
|Estimated Study Completion Date:||December 2013|
|Primary Completion Date:||January 2013 (Final data collection date for primary outcome measure)|
cancer patients with radiotherapy concerning the head and neck area/oral cavity
The "Dental Team" at the Department for Oral and Maxillofacial Surgery in Trondheim takes care of patients before, during and also after radiotherapy in the head and neck area. In spite of the use of advanced radiation protocols and prevention measures such as fluoridation splints the team observes significant side effects, both under radiation and also on the long term after concluding treatment. Common problems are for example dermal and mucosal damages, reduced salivation, dysphagia and lesions of the teeth. Aim of the study is the investigation and documentation of side effects and complications in relation to the oral cavity. During the acute and postradiation phase a continuous follow-up over a longer lasting period is proceeded with registration of all relevant parameters. This includes among others dental status and evaluation of quality of life.
|Department for Oral and Maxillofacial Surgery, St.Olavs Hospital / NTNU|
|Trondheim, Norway, 7006|
|Study Director:||Christoph M Ziegler, Prof.Dr.Dr.||St.Olavs Hospital / NTNU|