Impact of Non Invasive Ventilation on Quality of Sleep
Quality of sleep is profoundly affected in patients with hypercapnic respiratory failure and restrictive disorders, with a decrease in rapid eye movement (REM) and slow wave sleep, and an increase in sleep fragmentation. Assisted ventilation aims at improving blood gases, but may also have a favorable impact on sleep structure. The investigators reviewed polysomnographic and blood gas data obtained between 1987 and 2008 in 95 patients with restrictive pulmonary disorders, before and after implementing non-invasive ventilatory support.
Restrictive Pulmonary Disorders
Non Invasive Ventilation
|Study Design:||Observational Model: Case-Only
Time Perspective: Retrospective
|Official Title:||Impact of Non Invasive Ventilation on Quality of Sleep|
- Daytime arterial blood gases and Polysomnography before and after non invasive ventilation [ Time Frame: Average of 4 months ] [ Designated as safety issue: No ]
|Study Start Date:||January 1987|
|Study Completion Date:||December 2008|
|Primary Completion Date:||December 2008 (Final data collection date for primary outcome measure)|
Chronic respiratory failure
Patients with restrictive pulmonary disorders leading to progressive hypercapnic respiratory failure and requiring nocturnal non-invasive ventilation
Chart review of all patients with predominantly restrictive pulmonary disorders treated for respiratory failure by NIV at our institution between 1987 and 2008.
Data systematically recorded included pulmonary function tests, diurnal arterial blood gases, and polysomnography before and after implementation of nocturnal NIV.
|Study Director:||Daniel Rodenstein, Professor||Cliniques universitaires Saint-Luc- Université Catholique de Louvain|