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The Effect of Whey Protein on Short-Term Food Intake and Post-Meal Blood Glucose Response in Young Men

This study has been completed.
Sponsor:
Collaborators:
Natural Sciences and Engineering Research Council, Canada
Mondelēz International, Inc.
Information provided by:
University of Toronto
ClinicalTrials.gov Identifier:
NCT00988377
First received: September 30, 2009
Last updated: October 1, 2009
Last verified: October 2009
History of Changes
  Purpose

The objective of this study was to describe relationships among whey protein when consumed before a meal on food intake and pre- and post-meal satiety, blood glucose in healthy young adults.


Condition Intervention
Diabetes Prevention
Obesity Prevention
 Other: dietary intervention
Other: water control

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Crossover Assignment
Masking: Single Blind (Subject)
Primary Purpose: Prevention
Official Title: The Effect of Whey Protein on Short-term Food Intake and Post-meal Blood Glucose Response in Young Men

Resource links provided by NLM:

Drug Information available for: Dextrose
U.S. FDA Resources

Further study details as provided by University of Toronto:

Primary Outcome Measures:
  • Blood glucose subjective appetite Food intake at 30 min [ Time Frame: 0-95 min ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • physical comfort palatability [ Time Frame: 0-95 min ] [ Designated as safety issue: No ]

Enrollment: 16
Study Start Date: May 2007
Study Completion Date: November 2007
Primary Completion Date: August 2007 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: 10 g whey protein Other: dietary intervention
whey protein 10-40 g
Experimental: 20 g whey protein Other: dietary intervention
whey protein 10-40 g
Experimental: 30 g whey protein Other: dietary intervention
whey protein 10-40 g
Experimental: 40 g whey protein Other: dietary intervention
whey protein 10-40 g
Experimental: water control
Iso-volumetric (300 ml) water control (Crystal Springs, Canada)
 Other: water control
Iso-volumetric (300 ml) water control (Crystal Springs, Canada)

Detailed Description:

A randomized, cross-over design study was conducted. Whey protein preloads (10-40 g) were provided in 300 ml water. At 30 min following consumption, subjects were fed an ad libitum pizza meal. Satiety, and blood glucose were measured at baseline and selected intervals pre- (0, 15 and 30 min) and post-meal (50, 65, 80 and 95 min).

  Eligibility

Ages Eligible for Study:   20 Years to 27 Years
Genders Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • healthy
  • normal weight ( 18-24.9 kg/m²)
  • young aged 20-27 year old

Exclusion Criteria:

  • breakfast skippers
  • smokers
  • dieters
  • individuals with diabetes (fasting BG ≥ 7.0 mmol/L) or other metabolic diseases
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00988377

Locations
Canada, Ontario
University of Toronto, Department of Nutritional Sciences
Toronto, Ontario, Canada, M5S 3E2
Sponsors and Collaborators
University of Toronto
Natural Sciences and Engineering Research Council, Canada
Mondelēz International, Inc.
Investigators
Principal Investigator: Harvey Anderson, Ph.D. University of Toronto
  More Information

No publications provided by University of Toronto

Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):

Responsible Party: Dr. G. Harvey Anderson, University of Toronto
ClinicalTrials.gov Identifier: NCT00988377     History of Changes
Other Study ID Numbers: Kraft_whey protein: study 1
Study First Received: September 30, 2009
Last Updated: October 1, 2009
Health Authority: Canada: Ethics Review Committee

Keywords provided by University of Toronto:
whey protein
subjective appetite
shor-term food intake
blood glucose

Additional relevant MeSH terms:
Obesity
Overnutrition
Nutrition Disorders
 Overweight
Body Weight
Signs and Symptoms

ClinicalTrials.gov processed this record on May 16, 2013