S-100B and Neuron-specific Enolase (NSE) in Spinal Trauma (WBS)

This study has been completed.
Sponsor:
Information provided by:
Medical University of Vienna
ClinicalTrials.gov Identifier:
NCT00980434
First received: September 18, 2009
Last updated: April 3, 2012
Last verified: July 2011
  Purpose

The investigators are studying the clinical worth of the serum markers S-100B and NSE in patients with spinal cord injuries e.g. in patients with vertebral fractures. If there is a injury to the neuronal structures these two proteins could be secreted into the serum and add evidence to the severity of the injury.


Condition
Spinal Cord Injury

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: The Clinical Use of S-100B and NSE in Spinal Cord Injuries

Resource links provided by NLM:


Further study details as provided by Medical University of Vienna:

Primary Outcome Measures:
  • Neurological Symptoms [ Time Frame: 2 weeks ] [ Designated as safety issue: No ]

Biospecimen Retention:   Samples Without DNA

Serum probe


Enrollment: 60
Study Start Date: February 2008
Study Completion Date: December 2011
Primary Completion Date: November 2011 (Final data collection date for primary outcome measure)
Groups/Cohorts
1
patients with neurological symptoms
2
patients without neurological symptoms

  Eligibility

Ages Eligible for Study:   1 Year and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

patients from daily practice

Criteria

Inclusion Criteria:

  • vertebral fracture
  • injuries to the vertebral spine

Exclusion Criteria:

  • head trauma
  • polytrauma
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00980434

Locations
Austria
Medical University of Vienna
Vienna, Austria, 1090
Sponsors and Collaborators
Medical University of Vienna
Investigators
Study Chair: Vilmos Vecsei, M.D. Professor Head of Department
  More Information

Publications:
Responsible Party: Wolf Harald Dr., Department for Trauma Surgery
ClinicalTrials.gov Identifier: NCT00980434     History of Changes
Other Study ID Numbers: Wolf-4
Study First Received: September 18, 2009
Last Updated: April 3, 2012
Health Authority: Austria : Federal Ministry for Labour, Health, and Social Affairs

Keywords provided by Medical University of Vienna:
vertebral fracture
spinal cord injury

Additional relevant MeSH terms:
Spinal Cord Injuries
Wounds and Injuries
Spinal Cord Diseases
Central Nervous System Diseases
Nervous System Diseases
Trauma, Nervous System

ClinicalTrials.gov processed this record on April 16, 2014