Gene - Exercise Research Study (GERS)

This study has been completed.
Sponsor:
Collaborator:
University of Pittsburgh
Information provided by:
University of Maryland
ClinicalTrials.gov Identifier:
NCT00976742
First received: September 11, 2009
Last updated: NA
Last verified: September 2009
History: No changes posted
  Purpose

The investigators hypothesize that the degree to which older generally healthy but sedentary men and women improve a number of cardiovascular (CV) disease risk factors with 6 months of highly-standardized endurance exercise training will be a function of common genetic variations in candidate genes.


Condition Intervention
Cardiovascular Disease Risk Factors
Behavioral: Endurance exercise training

Study Type: Interventional
Study Design: Intervention Model: Single Group Assignment
Primary Purpose: Prevention
Official Title: Impact of Common Genetic Polymorphisms on CV Disease Risk Factor Changes With Endurance Exercise Training

Resource links provided by NLM:


Further study details as provided by University of Maryland:

Primary Outcome Measures:
  • Cardiovascular Disease Risk Factors [ Time Frame: ~9 months ] [ Designated as safety issue: No ]

Enrollment: 225
Study Start Date: June 1998
Primary Completion Date: December 2004 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Endurance Exercise Training Behavioral: Endurance exercise training

  Eligibility

Ages Eligible for Study:   50 Years to 75 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • generally healthy
  • free from CV disease
  • ability to undergo exercise training

Exclusion Criteria:

  • previous history of CV disease
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00976742

Locations
United States, Maryland
University of Maryland Dept of Kinesiology
College Park, Maryland, United States, 20742-2611
Sponsors and Collaborators
University of Maryland
University of Pittsburgh
  More Information

Publications:
Responsible Party: James Hagberg, PhD, Professor, Principal Investigator, University of Maryland College Park
ClinicalTrials.gov Identifier: NCT00976742     History of Changes
Other Study ID Numbers: AG17474
Study First Received: September 11, 2009
Last Updated: September 11, 2009
Health Authority: United States: Institutional Review Board

Keywords provided by University of Maryland:
plasma lipoprotein lipids
body composition
glucose tolerance
inflammation markers
insulin sensitivity
coagulation markers

Additional relevant MeSH terms:
Cardiovascular Diseases

ClinicalTrials.gov processed this record on August 01, 2014