Gene - Exercise Research Study (GERS)

This study has been completed.
University of Pittsburgh
Information provided by:
University of Maryland Identifier:
First received: September 11, 2009
Last updated: NA
Last verified: September 2009
History: No changes posted

The investigators hypothesize that the degree to which older generally healthy but sedentary men and women improve a number of cardiovascular (CV) disease risk factors with 6 months of highly-standardized endurance exercise training will be a function of common genetic variations in candidate genes.

Condition Intervention
Cardiovascular Disease Risk Factors
Behavioral: Endurance exercise training

Study Type: Interventional
Study Design: Intervention Model: Single Group Assignment
Primary Purpose: Prevention
Official Title: Impact of Common Genetic Polymorphisms on CV Disease Risk Factor Changes With Endurance Exercise Training

Resource links provided by NLM:

Further study details as provided by University of Maryland:

Primary Outcome Measures:
  • Cardiovascular Disease Risk Factors [ Time Frame: ~9 months ] [ Designated as safety issue: No ]

Enrollment: 225
Study Start Date: June 1998
Primary Completion Date: December 2004 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Endurance Exercise Training Behavioral: Endurance exercise training


Ages Eligible for Study:   50 Years to 75 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • generally healthy
  • free from CV disease
  • ability to undergo exercise training

Exclusion Criteria:

  • previous history of CV disease
  Contacts and Locations
Please refer to this study by its identifier: NCT00976742

United States, Maryland
University of Maryland Dept of Kinesiology
College Park, Maryland, United States, 20742-2611
Sponsors and Collaborators
University of Maryland
University of Pittsburgh
  More Information

Responsible Party: James Hagberg, PhD, Professor, Principal Investigator, University of Maryland College Park Identifier: NCT00976742     History of Changes
Other Study ID Numbers: AG17474
Study First Received: September 11, 2009
Last Updated: September 11, 2009
Health Authority: United States: Institutional Review Board

Keywords provided by University of Maryland:
plasma lipoprotein lipids
body composition
glucose tolerance
inflammation markers
insulin sensitivity
coagulation markers

Additional relevant MeSH terms:
Cardiovascular Diseases processed this record on April 17, 2014