The Effect of Periodontal Treatment on the Level of Free Radicals in the Saliva
Recruitment status was Recruiting
This study will examine the relationship between free radicals in the saliva and periodontitis. 30 adults, 15 with periodontitis and 15 as a control group will give a sample of saliva before treatment and after treatment. The investigators will examine the free radicals in both groups.
|Study Design:||Observational Model: Case Control
Time Perspective: Prospective
|Official Title:||The Effect of Periodontal Treatment on the Level of Free Radicals in the Saliva|
|Study Start Date:||July 2009|
|Estimated Primary Completion Date:||December 2010 (Final data collection date for primary outcome measure)|
Periodontal disease is a chronic adult condition. Bacteria implicated in the etiology of this disease causes destruction of connective tissue and bone. As a result of stimulation by bacterial antigen PMN produces free radicals via respiratory burst as a part of host response to infection.
Free radicals can be defined as molecules or molecular fragments with an unpaired electron which imparts certain characteristics to the free radicals such as reactivity . Reactive free radicals are able to produce chemical modifications and to damage proteins, lipids, carbohydrates and nucleotides in the tissues.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00969241
|department of oral and maxillofacial surgery, Baruch Padeh Medical Center||Recruiting|
|Tieberia, Israel, Poria, Israel|
|Contact: Eran Front, Dr. DMD 972-046652254 firstname.lastname@example.org|
|Contact: reem younis, Dr. 972-54- 4860977 email@example.com|
|Principal Investigator: Eran Front, Dr.|
|Sub-Investigator: Tsvika laster, Dr. DMD|
|Sub-Investigator: REEM YOUNIS, DMD|
|Principal Investigator:||eran front, Dr.||department of oral and maxillofacial surgery|