Study of Tissue Samples From Patients With Glioma or Other Brain Tumors
The recruitment status of this study is unknown because the information has not been verified recently.
Verified August 2009 by National Cancer Institute (NCI).
Recruitment status was Recruiting
Recruitment status was Recruiting
Sponsor:
University Hospital, Montpellier
Information provided by:
National Cancer Institute (NCI)
ClinicalTrials.gov Identifier:
NCT00967200
First received: August 26, 2009
Last updated: April 20, 2010
Last verified: August 2009
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Purpose
RATIONALE: Studying the genes expressed in samples of tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. It may also help doctors predict how patients will respond to treatment.
PURPOSE: This research study is looking at tissue samples from patients with glioma or other brain tumors.
| Condition | Intervention |
|---|---|
|
Brain and Central Nervous System Tumors |
Other: laboratory biomarker analysis Other: pharmacogenomic studies |
| Study Type: | Observational |
| Official Title: | Identification of Genes Involved in the Pathogenesis of Gliomas by Transcriptome Analysis |
Resource links provided by NLM:
Further study details as provided by National Cancer Institute (NCI):
Primary Outcome Measures:
- Pathophysiology of gliomas and identification of molecular markers that may predict prognosis and progression or that could identify new therapeutic approaches [ Designated as safety issue: No ]
| Estimated Enrollment: | 150 |
| Study Start Date: | November 2003 |
| Estimated Primary Completion Date: | December 2008 (Final data collection date for primary outcome measure) |
OBJECTIVES:
Primary
- To better understand the pathophysiology of gliomas and identify molecular markers that may predict prognosis and progression or that could identify new therapeutic approaches.
Secondary
- To compare gene expression profiles, in terms of response to treatment, and attempt to isolate subgroups of patients with objective response to certain types of chemotherapy or radiotherapy.
OUTLINE: This is a multicenter study.
Biological samples are collected from patients at time of surgery for diagnostic and/or treatment purposes.
Eligibility| Ages Eligible for Study: | 18 Years and older |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
Criteria
DISEASE CHARACTERISTICS:
Histologically confirmed glioma of any grade or rare primary brain tumor
- Planning surgery to remove the tumor
PATIENT CHARACTERISTICS:
- No urgent situation
- No known or suspected active infection
- Must not be deprived of liberty or protected by law
- Not pregnant or nursing
PRIOR CONCURRENT THERAPY:
- No concurrent participation in other trials that require a period of exclusion
Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00967200
Locations
| France | |
| CHU Montpellier | Recruiting |
| Montpellier, France, 34295 | |
| Contact: Luc Bauchet, MD Not Available | |
| Clinique Gui de Chauliac | Recruiting |
| Montpellier, France, 34295 | |
| Contact: Luc Bauchet, MD 33-67-542-494 | |
Sponsors and Collaborators
University Hospital, Montpellier
Investigators
| Investigator: | Luc Bauchet, MD | University Hospital, Montpellier |
More Information
No publications provided
| ClinicalTrials.gov Identifier: | NCT00967200 History of Changes |
| Other Study ID Numbers: | CDR0000626732, CHUM-DGS-2003/0402, CHUM-UF7745, INCA-RECF0467 |
| Study First Received: | August 26, 2009 |
| Last Updated: | April 20, 2010 |
| Health Authority: | Unspecified |
Keywords provided by National Cancer Institute (NCI):
|
adult anaplastic ependymoma adult anaplastic astrocytoma adult diffuse astrocytoma adult glioblastoma adult giant cell glioblastoma adult gliosarcoma adult pilocytic astrocytoma adult pineal gland astrocytoma adult subependymal giant cell astrocytoma adult brain stem glioma adult choroid plexus tumor adult craniopharyngioma adult ependymoblastoma adult medulloblastoma adult supratentorial primitive neuroectodermal tumor (PNET) |
adult ependymoma adult myxopapillary ependymoma adult subependymoma meningeal melanocytoma adult meningeal hemangiopericytoma adult grade I meningioma adult grade II meningioma adult anaplastic meningioma adult papillary meningioma adult anaplastic oligodendroglioma adult oligodendroglioma adult pineoblastoma adult pineocytoma adult mixed glioma recurrent adult brain tumor |
Additional relevant MeSH terms:
|
Brain Neoplasms Glioma Nervous System Neoplasms Central Nervous System Neoplasms Neoplasms by Site Neoplasms Brain Diseases Central Nervous System Diseases |
Nervous System Diseases Neoplasms, Neuroepithelial Neuroectodermal Tumors Neoplasms, Germ Cell and Embryonal Neoplasms by Histologic Type Neoplasms, Glandular and Epithelial Neoplasms, Nerve Tissue |
ClinicalTrials.gov processed this record on May 22, 2013