Salivary Bacteria and Oral Health Status in Children With ADHD

This study has been completed.
Sponsor:
Information provided by:
Hadassah Medical Organization
ClinicalTrials.gov Identifier:
NCT00966394
First received: August 25, 2009
Last updated: May 25, 2010
Last verified: August 2009
  Purpose

Attention deficit and hyperactivity (ADHD) affect 6% of school-aged children. Few studies reported higher prevalence of caries and restorations among children with ADHD. Methylphenidate is the drug of choice to treat ADHD. according to the medical literature methylphenidate can cause xerostomia.

Our study will investigate saliva parameters (such as quantity, bacteria in saliva, buffer capacity), oral hygiene and diet habits and their influence on caries among children with ADHD and among healthy children.

Our hypothesis is:

  • Children with ADHD will have more caries.
  • Children with ADHD will have more detrimental oral hygiene and diet habits.
  • There will be a difference in the saliva parameters between children with ADHD and healthy children.

Condition
Attention Deficit Hyperactivity Disorders
Caries, Dental
Xerostomia

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Cross-Sectional
Official Title: Changes in Salivary Bacteria and Oral Health Status in Children With Attention Deficit Hyperactivity Disorder (ADHD)

Resource links provided by NLM:


Further study details as provided by Hadassah Medical Organization:

Biospecimen Retention:   None Retained

saliva


Estimated Enrollment: 150
Study Start Date: November 2009
Study Completion Date: May 2010
Primary Completion Date: May 2010 (Final data collection date for primary outcome measure)
Groups/Cohorts
ADHD medication
Children with ADHD and pharmacologic treatment
ADHD without medication
Children with ADHD without pharmacologic treatment
healthy
Healthy children ASA1

  Eligibility

Ages Eligible for Study:   5 Years to 18 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

Children with ADHD, treated by medications or not, treated in the neurologic clinic at Hadassah.

The control are healthy children visiting the pediatric dental clinic at Hadassah.

Criteria

Inclusion Criteria:

  • test group- diagnosis of ADHD.
  • control group- ASA1

Exclusion Criteria:

  • control group
  • administration of medicine at the time of the check-up.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00966394

Locations
Israel
Hadassah school of dental medicine
Jerusalem, Israel, 91120
Sponsors and Collaborators
Hadassah Medical Organization
  More Information

No publications provided

Responsible Party: Dr. Moti Moskovitz, Department of Pediatric Dentistry, Hadassah School of Dental Medicine
ClinicalTrials.gov Identifier: NCT00966394     History of Changes
Other Study ID Numbers: adhd-hmo-ctil
Study First Received: August 25, 2009
Last Updated: May 25, 2010
Health Authority: Israel: Ministry of Health

Keywords provided by Hadassah Medical Organization:
ADHD, saliva, caries

Additional relevant MeSH terms:
Attention Deficit Disorder with Hyperactivity
Hyperkinesis
Disease
Xerostomia
Dental Caries
Attention Deficit and Disruptive Behavior Disorders
Mental Disorders Diagnosed in Childhood
Mental Disorders
Dyskinesias
Neurologic Manifestations
Nervous System Diseases
Signs and Symptoms
Pathologic Processes
Salivary Gland Diseases
Mouth Diseases
Stomatognathic Diseases
Tooth Demineralization
Tooth Diseases

ClinicalTrials.gov processed this record on October 01, 2014