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Spirometry in Mechanically Ventilated Chronic Obstructive Pulmonary Disease (COPD) Patients

The recruitment status of this study is unknown because the information has not been verified recently.
Verified August 2009 by Assaf-Harofeh Medical Center.
Recruitment status was  Not yet recruiting
Sponsor:
Information provided by:
Assaf-Harofeh Medical Center
ClinicalTrials.gov Identifier:
NCT00965029
First received: August 24, 2009
Last updated: April 4, 2011
Last verified: August 2009
History of Changes
  Purpose

Patients with COPD who deteriorate to Respiratory Failure pose a challenge to the intensivist both in ventilating an obstructed patient and in weaning from mechanical ventilation.

Currently there are no accepted extubation criteria in COPD patients that could predict successful weaning from mechanical ventilation. In this study we will attempt to correlate spirometric data to eventual weaning from mechanical ventilation.


Condition
COPD

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Spirometry in Mechanically Ventilated COPD Patients: Correlation of Lung Function Tests to Successful Weaning From Mechanical Ventilation

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by Assaf-Harofeh Medical Center:

Estimated Enrollment: 100
Study Start Date: September 2009
Estimated Study Completion Date: September 2012
Estimated Primary Completion Date: September 2012 (Final data collection date for primary outcome measure)
Detailed Description:

COPD patients who deteriorate to Respiratory Failure will be recruited. Sedation will be interrupted daily, and each day once the patient is awake and cooperative, spirometry will be performed. FEV1 and FVC will be recorded and later correlated to eventual rate of successful extubation.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

COPD patients with respiratory failure due to COPD exacerbation, and on mechanical ventilation

Criteria

Inclusion Criteria:

  • >18
  • Mechanically ventilated due to COPD exacerbation

Exclusion Criteria:

  • decreased level of consciousness
  • uncooperative patient
  • Bronchial asthma
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00965029

Contacts
Contact: Arie Soroksky, MD 972-8-9779320 soroksky@gmail.com

Locations
Israel
Arie Soroksky Not yet recruiting
Beer Yaakov, Zerifin, Israel, 70300
Contact: Arie Soroksky, MD     972-8-9779320     soroksky@gmail.com    
Sponsors and Collaborators
Assaf-Harofeh Medical Center
Investigators
Principal Investigator: Arie Soroksky, MD General ICU, Assaf Harofe MC, Zerifin, Israel
  More Information

No publications provided

Responsible Party: Arie Soroksky, M.D., General ICU, Assaf Harofe Medical Center, Zerifin 70300, Israel
ClinicalTrials.gov Identifier: NCT00965029     History of Changes
Other Study ID Numbers: 101/09
Study First Received: August 24, 2009
Last Updated: April 4, 2011
Health Authority: Israel: Ethics Commission

Keywords provided by Assaf-Harofeh Medical Center:
COPD
Spirometry
Weaning

Additional relevant MeSH terms:
Lung Diseases
Pulmonary Disease, Chronic Obstructive
Lung Diseases, Obstructive
Respiratory Tract Diseases

ClinicalTrials.gov processed this record on June 18, 2013