Preventive Medicine Study of Childhood Atopic Diseases
Under environmental intervention programs, to explore the associations between Environmental Tobacco Smoke (ETS) and changes of pulmonary function, cytokines and new-onset asthma between different groups.
|Study Design:||Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single Blind (Subject)
Primary Purpose: Health Services Research
|Official Title:||Preventive Medicine Study of Childhood Atopic Diseases|
- urine cotinine level [ Time Frame: six months, one year ] [ Designated as safety issue: No ]
|Study Start Date:||July 2009|
|Estimated Study Completion Date:||June 2010|
|Estimated Primary Completion Date:||June 2010 (Final data collection date for primary outcome measure)|
Behavioral: Health promotion and health education for smoking habits
Environmental intervention programs:
We will both interview by telephone and mail the health education leaflets, in order to achieve the following aims:
-Smokers living with the children will change where smoking takes place for reducing the children's ETS exposure.
We will contact participants individually to get informed consent before data collection. No matter what intervention, non-intervention or reference group, all participants will test as follows:
- Blood sample collection: We will test the total IgE, specific IgE, cytokines, such as IL-4, IL-13, TNF-α, ECP and EOS.
- Questionnaire collection
- Pulmonary function test
After intervention programs applied, all participants will test pulmonary function, and total IgE, specific IgE and cytokines by blood sample after six months by school approaches. Then, we can compare the pulmonary function, total IgE, specific IgE and cytokines before and after intervention programs.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00960596
|National Taiwan University|
|Taipei, Taiwan, 10020|
|Principal Investigator:||YungLing Lee, Dr.||Institute of Preventive Medicine, College of Public Health, National Taiwan University|