Cancer Pain Single Nucleotide Polymorphisms (SNPs)

The recruitment status of this study is unknown because the information has not been verified recently.
Verified June 2011 by Erasmus Medical Center.
Recruitment status was  Recruiting
Sponsor:
Information provided by:
Erasmus Medical Center
ClinicalTrials.gov Identifier:
NCT00956878
First received: August 10, 2009
Last updated: June 21, 2011
Last verified: June 2011
  Purpose

Cancer pain is common in advanced cancer patients. Opioids are the mainstay of treatment in cancer pain. Responsiveness to and tolerability of opioids is, amongst others, determined by small variations in human DNA. Using blood samples from clinically well-defined cancer pain patients, the investigators are going to analyze single nucleotide polymorphisms (SNPs) in genes that are known to be involved in responsiveness to opioids and sensitivity to pain.


Condition
Cancer
Pain

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Storage and Analysis of Patient Blood-samples for Cancer Pain Research

Resource links provided by NLM:


Further study details as provided by Erasmus Medical Center:

Biospecimen Retention:   Samples With DNA

Whole Blood


Estimated Enrollment: 300
Study Start Date: September 2008
Estimated Study Completion Date: September 2012
Estimated Primary Completion Date: September 2012 (Final data collection date for primary outcome measure)
Groups/Cohorts
Cancer Pain Patients

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

Cancer pain patients in a large university hospital

Criteria

Inclusion Criteria:

  • Cancer pain patients

Exclusion Criteria:

  • Patients not able to provide informed consent
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00956878

Locations
Netherlands
Erasmus MC, Centrumlocatie en Daniel den Hoed Recruiting
Rotterdam, Zuid-Holland, Netherlands, 3000CA
Contact: Joost L Jongen, MD PhD    +31107035754    j.jongen@erasmusmc.nl   
Contact: Peter A Sillevis-Smitt, MD PhD    +317033327    p.sillevissmitt@erasmusmc.nl   
Principal Investigator: Joost L Jongen, MD PhD         
Sponsors and Collaborators
Erasmus Medical Center
Investigators
Principal Investigator: Joost L Jongen, MD PhD Erasmus MC
  More Information

Additional Information:
No publications provided

Responsible Party: Joost L.M. Jongen, MD PhD, Erasmus MC
ClinicalTrials.gov Identifier: NCT00956878     History of Changes
Other Study ID Numbers: MEC2008-166
Study First Received: August 10, 2009
Last Updated: June 21, 2011
Health Authority: Netherlands: Dutch Health Care Inspectorate

Keywords provided by Erasmus Medical Center:
Cancer
Pain
SNP

ClinicalTrials.gov processed this record on April 22, 2014