Plasma Pharmacokinetics of Alkylresorcinol Metabolites; New Candidate Biomarkers for Whole Grain Rye and Wheat Intake (Rye-kinetics)

This study has been completed.
Sponsor:
Collaborators:
Samfundet Folkhälsan
Sigrid Jusélius Foundation
Information provided by:
Helsinki University
ClinicalTrials.gov Identifier:
NCT00953836
First received: August 5, 2009
Last updated: NA
Last verified: August 2009
History: No changes posted
  Purpose

The purpose of this study is to investigate the kinetics of two known alkylresorcinol metabolites in human subjects after intake of high-fiber rye bread. Whole grain rye is the most abundant source of alkylresorcinols.


Condition
Kinetics of Alkylresorcinol Metabolites

Study Type: Observational
Study Design: Time Perspective: Prospective
Official Title: Kinetic Study of Two Known Alkylresorcinol Metabolites in Human Subjects After the Intake of Rye Fiber, the Most Abundant Source of Alkylresorcinols in Diet.

Resource links provided by NLM:


Further study details as provided by Helsinki University:

Enrollment: 15
Study Start Date: March 2009
Study Completion Date: May 2009
Primary Completion Date: April 2009 (Final data collection date for primary outcome measure)
  Eligibility

Ages Eligible for Study:   20 Years to 65 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

healthy, free-living females and males

Criteria

Inclusion Criteria:

  • Healthy, volunteer

Exclusion Criteria:

  • Hemoglobin below 125 mmol/L in females and below 135 mmol/L in males use of antibiotics within 3 months before entering the study
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00953836

Locations
Finland
Folkhälsan Research Center
Helsinki, Finland, 00250
Sponsors and Collaborators
Helsinki University
Samfundet Folkhälsan
Sigrid Jusélius Foundation
Investigators
Study Director: Matti J Tikkanen, M.D., prof. Department of Medicine, University of Helsinki, Helsinki, Finland
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00953836     History of Changes
Other Study ID Numbers: 22/13/03/00/09
Study First Received: August 5, 2009
Last Updated: August 5, 2009
Health Authority: Finland: Ethics Committee

Keywords provided by Helsinki University:
kinetics
alkylresorcinol metabolites
rye fiber

ClinicalTrials.gov processed this record on July 20, 2014