Evaluation of the Quality of Cardio-Pulmonary Resuscitation (CPR) in Cardiac Arrest Patients
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
Purpose
The prognosis of cardiac arrest patients is generally poor. Recent studies have showed that the high quality of CPR increases the survival after cardiac arrest. Therefore the investigators planned this prospective observational study to determine the epidemiology of sudden cardiac arrest in the prehospital setting of Tampere area, the quality of the CPR, and also the associations between depth and frequency of chest compressions and invasive arterial pressure, EtCO2,cerebral oxygenation and iatrogenic injuries associated to chest compressions 1) in patients resuscitated out of hospital by emergency medical service's (EMS's) personals and 2) in-hospital by hospital resuscitation team members. In addition, the investigators will analyze the effects of the chosen method of resuscitation on critical vital signs (Etco2 and invasive pressures): closed-chest CPR is compared to open-chest CPR, or mechanical CPR with a device (AutoPulse-CPR, Cardio Pump) compared to manual CPR guided with quality CPR device. The results will give the investigators important insights into the haemodynamics of CPR which may guide future strategies for the management of cardiac arrest. The research group is also interested in CPR related injuries and mattress effect. Quality of life after CA is evaluated among survivals and the cause of death among non-survivors.
| Condition |
|---|
|
Cardiac Arrest |
| Study Type: | Observational |
| Study Design: | Observational Model: Cohort Time Perspective: Prospective |
| Official Title: | Evaluating the Quality of Prehospital and In-hospital Cardio-pulmonary Resuscitation by Reviewing Defibrillator Records - Comparing the Compressions to Concurrent Vital Signs (Invasive Blood Pressure, Cerebral Oxygen Saturation, EtCO2) and Iatrogenic Injuries Associated to Chest Compressions. |
- The success rate of current guidelines (depth and frequency of chest compression, epidemiology) [ Time Frame: During the resuscitation ] [ Designated as safety issue: No ]
- Quality of life after CA [ Time Frame: 6 months ] [ Designated as safety issue: No ]Quality of life after CA is usually fairly good measurement of quality of resuscitation attempt
- Invasive arterial pressures, cerebral oxygenation (NIRS), EtCO2 [ Time Frame: During the resuscitation ] [ Designated as safety issue: No ]
- survival of cardiac arrest [ Time Frame: hospital discharge ] [ Designated as safety issue: No ]
- Change in hemodynamics, Change in cerebral saturation, Change in quality of CPR [ Time Frame: During resuscitation ] [ Designated as safety issue: Yes ]
| Estimated Enrollment: | 500 |
| Study Start Date: | November 2008 |
| Estimated Study Completion Date: | December 2017 |
| Estimated Primary Completion Date: | December 2015 (Final data collection date for primary outcome measure) |
| Groups/Cohorts |
|---|
| Cardiac arrest |
Eligibility| Ages Eligible for Study: | 18 Years and older |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
| Sampling Method: | Probability Sample |
Adult population >18 years of age with cardiac arrest
Inclusion Criteria:
- cardiac arrest
- > 18 years of age
Exclusion Criteria:
- < 18 years of age
Contacts and Locations| Contact: Sanna Hoppu, MD, PhD | +358503624711 | sanna.hoppu@fimnet.fi |
| Contact: Marko Sainio, MD | +358505342399 | marko.sainio@fimnet.fi |
| Finland | |
| Critical Care Medicine Research Group, Tampere University Hospital | Recruiting |
| Tampere, Pirkanmaa, Finland, 33521 | |
| Contact: Sanna Hoppu, MD, PhD +358503624711 sanna.hoppu@fimnet.fi | |
| Contact: Marko Sainio, MB +358505342399 marko.sainio@fimnet.fi | |
| Department of Anesthesiology and Intensive Care, Turku University Hospital | Recruiting |
| Turku, Finland, 20100 | |
| Contact: Klaus Olkkola, MD, PhD +358407583655 klaus.olkkola@tyks.fi | |
| Study Director: | Jyrki Tenhunen, MD, PhD | Critical Care Medicine Research Group |
| Principal Investigator: | Sanna Hoppu, MD, PhD | Critical Care Medicine Research Group |
| Principal Investigator: | Marko Sainio, MD | Critical Care Medicine Research Group |
| Study Director: | Klaus Olkkola, MD, PhD | Turku University Hospital |
| Principal Investigator: | Heidi Hellevuo, MB | Critical Care Medicine Research Group |
| Principal Investigator: | Piritta Setälä, MD | Tampere University Hospital |
| Study Director: | Ilkka Virkkunen, MD, PhD | Tampere University Hospital |
More Information
No publications provided by Tampere University Hospital
Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
| Responsible Party: | Arvi Yli-Hankala, MD, PhD, Tampere University Hospital |
| ClinicalTrials.gov Identifier: | NCT00951704 History of Changes |
| Other Study ID Numbers: | R08116 |
| Study First Received: | July 31, 2009 |
| Last Updated: | April 15, 2013 |
| Health Authority: | Finland: Ethics Committee |
Keywords provided by Tampere University Hospital:
|
Open-chest CPR Tissue Perfusion invasive arterial pressure |
exhaled carbon dioxide Quality of life Quality of chest compressions Epidemiology of sudden cardiac arrest(OHCA) |
Additional relevant MeSH terms:
|
Heart Arrest Heart Diseases Cardiovascular Diseases |
ClinicalTrials.gov processed this record on May 19, 2013