Cassia Cinnamon for Glucose Uptake in Young Women

This study has been completed.
Sponsor:
Information provided by:
Baylor University
ClinicalTrials.gov Identifier:
NCT00951639
First received: August 3, 2009
Last updated: NA
Last verified: August 2009
History: No changes posted
  Purpose

The purpose of this study was to compare the acute effects of 5g of Cassia cinnamon, 50 minutes of endurance exercise performed at 70% of the heart rate reserve (correlated to VO2max), and 5g of cellulose placebo on blood glucose, serum insulin and insulin sensitivity following an oral glucose tolerance test 3 hours after administration of each intervention.


Condition Intervention
Insulin Resistance
Impaired Glucose Tolerance
Prediabetes
Dietary Supplement: Cassia cinnamon
Procedure: 50 minutes exercise
Dietary Supplement: Cellulose Powder

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Crossover Assignment
Masking: Double Blind (Subject, Investigator)
Primary Purpose: Supportive Care
Official Title: Cassia Cinnamon and Acute Endurance Exercise for the Enhancement of Glucose Uptake in Healthy Young Women

Resource links provided by NLM:


Further study details as provided by Baylor University:

Primary Outcome Measures:
  • Blood Glucose [ Time Frame: Baseline, 0, 30, 60, 90 and 120 minutes following OGTT ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Serum Insulin [ Time Frame: Baseline, 0, 30, 60, 90 and 120 minutes following OGTT ] [ Designated as safety issue: No ]

Enrollment: 10
Study Start Date: February 2008
Study Completion Date: May 2009
Primary Completion Date: May 2009 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: 5g Cassia cinnamon
Experimental treatment group
Dietary Supplement: Cassia cinnamon
5g encapsulated ground bark administered once in experimental session
Other Name: Brand: Nature's Bounty
Active Comparator: 50 minutes endurnace exercise
Endurance exercise treatment known to influence blood glucose
Procedure: 50 minutes exercise
50 minutes treadmill endurance exercise at 70% of the heart rate reserve (correlated to VO2max)
Placebo Comparator: 5g Cellulose
Placebo equivalent in weight and appearance to experimental treatment
Dietary Supplement: Cellulose Powder
5g encapsulated powder administered during placebo experimental session

  Eligibility

Ages Eligible for Study:   18 Years to 30 Years
Genders Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Sedentary
  • BMI: 27-45
  • DXA body fat % greater than 30%
  • 18-30 years of age
  • Healthy
  • From the Baylor University campus and surrounding community
  • Regular sleep habits

Exclusion Criteria:

  • Not regular users of any species of cinnamon
  • Not diagnosed with any metabolic disorder or chronic medical condition
  • Not taking prescription medications for 2 months before the study
  • Not taking ergogenic aids for 2 months before the study
  • Not taking oral contraceptives for 2 months before the study
  • No IUD placed for 2 months before the study
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00951639

Locations
United States, Texas
Baylor University Department of Health, Human Performance, and Recreation
Waco, Texas, United States, 76798
Sponsors and Collaborators
Baylor University
Investigators
Study Chair: Darryn S Willoughby, Ph.D. Baylor University
Principal Investigator: Jean L Gutierrez, Ph.D. Baylor University
  More Information

Publications:
Responsible Party: Darryn Willoughby, Baylor University Department of Health, Human Performance, and Recreation
ClinicalTrials.gov Identifier: NCT00951639     History of Changes
Other Study ID Numbers: BaylorU_Cassia_Women
Study First Received: August 3, 2009
Last Updated: August 3, 2009
Health Authority: United States: Institutional Review Board

Keywords provided by Baylor University:
Cassia
Cinnamon
Blood Glucose
Endurance exercise
Acute exercise
Overweight
Obesity
Women

Additional relevant MeSH terms:
Insulin Resistance
Glucose Intolerance
Prediabetic State
Hyperinsulinism
Glucose Metabolism Disorders
Metabolic Diseases
Hyperglycemia
Diabetes Mellitus
Endocrine System Diseases

ClinicalTrials.gov processed this record on August 20, 2014