Cassia Cinnamon for Glucose Uptake in Young Women

This study has been completed.
Information provided by:
Baylor University Identifier:
First received: August 3, 2009
Last updated: NA
Last verified: August 2009
History: No changes posted

The purpose of this study was to compare the acute effects of 5g of Cassia cinnamon, 50 minutes of endurance exercise performed at 70% of the heart rate reserve (correlated to VO2max), and 5g of cellulose placebo on blood glucose, serum insulin and insulin sensitivity following an oral glucose tolerance test 3 hours after administration of each intervention.

Condition Intervention
Insulin Resistance
Impaired Glucose Tolerance
Dietary Supplement: Cassia cinnamon
Procedure: 50 minutes exercise
Dietary Supplement: Cellulose Powder

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Crossover Assignment
Masking: Double Blind (Subject, Investigator)
Primary Purpose: Supportive Care
Official Title: Cassia Cinnamon and Acute Endurance Exercise for the Enhancement of Glucose Uptake in Healthy Young Women

Resource links provided by NLM:

Further study details as provided by Baylor University:

Primary Outcome Measures:
  • Blood Glucose [ Time Frame: Baseline, 0, 30, 60, 90 and 120 minutes following OGTT ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Serum Insulin [ Time Frame: Baseline, 0, 30, 60, 90 and 120 minutes following OGTT ] [ Designated as safety issue: No ]

Enrollment: 10
Study Start Date: February 2008
Study Completion Date: May 2009
Primary Completion Date: May 2009 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: 5g Cassia cinnamon
Experimental treatment group
Dietary Supplement: Cassia cinnamon
5g encapsulated ground bark administered once in experimental session
Other Name: Brand: Nature's Bounty
Active Comparator: 50 minutes endurnace exercise
Endurance exercise treatment known to influence blood glucose
Procedure: 50 minutes exercise
50 minutes treadmill endurance exercise at 70% of the heart rate reserve (correlated to VO2max)
Placebo Comparator: 5g Cellulose
Placebo equivalent in weight and appearance to experimental treatment
Dietary Supplement: Cellulose Powder
5g encapsulated powder administered during placebo experimental session


Ages Eligible for Study:   18 Years to 30 Years
Genders Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Sedentary
  • BMI: 27-45
  • DXA body fat % greater than 30%
  • 18-30 years of age
  • Healthy
  • From the Baylor University campus and surrounding community
  • Regular sleep habits

Exclusion Criteria:

  • Not regular users of any species of cinnamon
  • Not diagnosed with any metabolic disorder or chronic medical condition
  • Not taking prescription medications for 2 months before the study
  • Not taking ergogenic aids for 2 months before the study
  • Not taking oral contraceptives for 2 months before the study
  • No IUD placed for 2 months before the study
  Contacts and Locations
Please refer to this study by its identifier: NCT00951639

United States, Texas
Baylor University Department of Health, Human Performance, and Recreation
Waco, Texas, United States, 76798
Sponsors and Collaborators
Baylor University
Study Chair: Darryn S Willoughby, Ph.D. Baylor University
Principal Investigator: Jean L Gutierrez, Ph.D. Baylor University
  More Information

Responsible Party: Darryn Willoughby, Baylor University Department of Health, Human Performance, and Recreation Identifier: NCT00951639     History of Changes
Other Study ID Numbers: BaylorU_Cassia_Women
Study First Received: August 3, 2009
Last Updated: August 3, 2009
Health Authority: United States: Institutional Review Board

Keywords provided by Baylor University:
Blood Glucose
Endurance exercise
Acute exercise

Additional relevant MeSH terms:
Insulin Resistance
Glucose Intolerance
Prediabetic State
Glucose Metabolism Disorders
Metabolic Diseases
Diabetes Mellitus
Endocrine System Diseases processed this record on April 16, 2014