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The Acute Effects of Coffee on Glucose Metabolism

This study has been completed.
Sponsor:
Information provided by:
Brooklyn College of the City University of New York
ClinicalTrials.gov Identifier:
NCT00950898
First received: July 31, 2009
Last updated: NA
Last verified: July 2009
History: No changes posted
  Purpose

The purpose of this study was to determine the acute effects of decaffeinated coffee, caffeinated coffee and caffeine on glucose metabolism in humans


Condition Intervention
Type 2 Diabetes
 Other: decaff
Other: caffcoff
Other: caffeine
Other: placebo

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Single Blind (Subject)
Primary Purpose: Basic Science
Official Title: Human Trial of the Acute Effects of Coffee on Glucose Metabolism

Resource links provided by NLM:

Drug Information available for: Dextrose
U.S. FDA Resources

Further study details as provided by Brooklyn College of the City University of New York:

Primary Outcome Measures:
  • plasma glucose levels [ Time Frame: 0, 10, 30, 60, 90, and 120 minutes. ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • plasma insulin [ Time Frame: 0, 10, 30, 60, 90, and 120 minutes ] [ Designated as safety issue: No ]

Enrollment: 11
Study Start Date: November 2006
Study Completion Date: June 2007
Primary Completion Date: June 2007 (Final data collection date for primary outcome measure)
Intervention Details:
    Other: decaff
    2 mugs of decaffeinated coffee
    Other: caffcoff
    2 mugs of caffeinated coffee
    Other: caffeine
    2 mugs of hot water containing caffeine
    Other: placebo
    2 mugs of hot water
  Eligibility

Ages Eligible for Study:   18 Years to 35 Years
Genders Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • healthy young males
  • nonsmokers
  • moderate alcohol users

Exclusion Criteria:

  • not on any medications that could alter glucose metabolism
  • no history of blood disorders
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00950898

Locations
United States, New York
Brooklyn College of the City University of New York
Brooklyn, New York, United States, 11210
Sponsors and Collaborators
Brooklyn College of the City University of New York
Investigators
Principal Investigator: James Greenberg, Ph.D. Brooklyn College of the City University of New York
  More Information

No publications provided

Responsible Party: James Greenberg, PhD., Principal Investigator, Brooklyn College of the City University of New York
ClinicalTrials.gov Identifier: NCT00950898     History of Changes
Other Study ID Numbers: 07-020
Study First Received: July 31, 2009
Last Updated: July 31, 2009
Health Authority: United States: Institutional Review Board

Keywords provided by Brooklyn College of the City University of New York:
coffee
caffeine
glucose metabolism
insulin sensitivity
diabetes

Additional relevant MeSH terms:
Diabetes Mellitus
Diabetes Mellitus, Type 2
Glucose Metabolism Disorders
Metabolic Diseases
Endocrine System Diseases
Caffeine
Central Nervous System Stimulants
Physiological Effects of Drugs
Pharmacologic Actions
 Central Nervous System Agents
Therapeutic Uses
Phosphodiesterase Inhibitors
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action
Purinergic P1 Receptor Antagonists
Purinergic Antagonists
Purinergic Agents
Neurotransmitter Agents

ClinicalTrials.gov processed this record on May 19, 2013