Evaluation of Plasma Catecholamine Concentration During Surgery
Recruitment status was Active, not recruiting
Stress during surgery leads to significant increase in plasma catecholamine concentrations in surgeons, anesthesiologists, and patients.
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Evaluation of Stress Hormone Concentration During the Resection of Pheochromocytoma. Comparison of Surgeon - Anesthesiologist - Patient|
Venous blood will be drawn from the surgeon, anesthesiologist and from 8 patients to determine plasma catecholamine concentrations. Only plasma will be used for measurements.
|Study Start Date:||June 2009|
|Estimated Study Completion Date:||September 2010|
|Estimated Primary Completion Date:||July 2010 (Final data collection date for primary outcome measure)|
To detect the degree of intraoperative stress, venous blod will be drawn from one surgeon during 8 pheochromocytoma resections.
To detect the degree of intraoperative stress, venous blood will be drawn from one anesthesiologist during 8 pheochromocytoma resections.
Patients with pheochromocytoma
Venous blood will be drawn from 8 patients with pheochromocytoma during tumor resection.
Hypothesis: Resection of pheochromocytomas can lead to more than normal stress in surgeons and because of abrupt hemodynamic changes in patients as well in anesthesiologists. Measurements of catecholamine concentrations at baseline, prior to surgery during and after surgery, are to be performed to test this hypothesis.