Tooth Mousse and Fluoride in Dentin Hypersensitivity Treatment

This study has been completed.
Sponsor:
Collaborator:
National Natural Science Foundation of China
Information provided by:
Huazhong University of Science and Technology
ClinicalTrials.gov Identifier:
NCT00926484
First received: June 22, 2009
Last updated: NA
Last verified: June 2009
History: No changes posted
  Purpose

GC Tooth Mousse, a complex containing amorphous calcium phosphate (ACP) and casein phosphopeptide (CPP), is recommended in dentin hypersensitivity reduction due to its ability to block opened dentinal tubules. It acts synergistically with fluorine in slowing caries progression. Whether CPP-ACP can act synergistically with fluorine in the dentin hypersensitivity treatment is unknown. The aim of this study was to assess the effect of CPP-ACP combined with fluoride varnish in cervical dentin hypersensitivity treatment.


Condition
Dentin Hypersensitivity

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Retrospective
Official Title: Combined Tooth Mousse and Fluoride Varnish in Dentin Hypersensitivity Treatment

Resource links provided by NLM:


Further study details as provided by Huazhong University of Science and Technology:

Primary Outcome Measures:
  • ANOVA [ Time Frame: June 2008 ] [ Designated as safety issue: Yes ]

Secondary Outcome Measures:
  • T-test [ Time Frame: June 2008 ] [ Designated as safety issue: Yes ]

Enrollment: 30
Study Start Date: January 2007
Study Completion Date: June 2008
Primary Completion Date: January 2008 (Final data collection date for primary outcome measure)
Groups/Cohorts
Tooth Mousse
fluoride varnish
Tooth Mousse + fluoride varnish

  Eligibility

Ages Eligible for Study:   26 Years to 66 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population

primary care clinic

Criteria

Inclusion Criteria:

  • subjects with a minimum of three cervical hypersensitive teeth at both sides of the dental arch

Exclusion Criteria:

  • dentin hypersensitivity caused by caries lesions
  • fracture of restoration
  • chipped teeth
  • marginal gaps
  • post-operative sensitivity
  • cracked-tooth syndrome, and which were confirmed by periapical radiographs and teeth with cervical fillings
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00926484

Locations
China, Hubei
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Wuhan, Hubei, China, 430030
Sponsors and Collaborators
Huazhong University of Science and Technology
National Natural Science Foundation of China
Investigators
Study Chair: Xuejin Tao, Doctor Huazhong University of Science and Technology
  More Information

Additional Information:
Publications:
Responsible Party: Weimin Chen, Tongji Hospital, Huazhong University of Science and Technology
ClinicalTrials.gov Identifier: NCT00926484     History of Changes
Other Study ID Numbers: TF87330244
Study First Received: June 22, 2009
Last Updated: June 22, 2009
Health Authority: China: National Natural Science Foundation

Keywords provided by Huazhong University of Science and Technology:
Dentin hypersensitivity
Tooth Mousse
fluoride varnish

Additional relevant MeSH terms:
Dentin Sensitivity
Hypersensitivity
Tooth Diseases
Stomatognathic Diseases
Immune System Diseases
Fluorides, Topical
Fluorides
Cariostatic Agents
Protective Agents
Physiological Effects of Drugs
Pharmacologic Actions

ClinicalTrials.gov processed this record on July 20, 2014