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Acute Effects of Acu-Transcutaneous Electrical Nerve Stimulation (Acu-TENS) on Forced Expiratory Flow Volume in One Second (FEV1) and Blood β-Endorphin Level in Subjects With Chronic Obstructive Pulmonary Disease (COPD)

This study has been completed.
Sponsor:
Information provided by:
The Hong Kong Polytechnic University
ClinicalTrials.gov Identifier:
NCT00922051
First received: June 16, 2009
Last updated: NA
Last verified: June 2009
History: No changes posted
  Purpose

The objective of this study is to investigate the effectiveness of Acu-TENS (transcutaneous electrical nerve stimulation applied on acupoints) on lung functions, dyspnoeic symptoms and its association with beta endorphin level in subjects with COPD.


Condition Intervention
Chronic Obstructive Pulmonary Disease (COPD)
 Device: Transcutaneous electrical nerve stimulation (TENS)

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor)
Primary Purpose: Supportive Care
Official Title: Acute Effects of Acu-TENS on FEV1 and Blood β-Endorphin Level in Subjects With COPD

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by The Hong Kong Polytechnic University:

Primary Outcome Measures:
  • Forced expiratory flow volume in one second (FEV1), forced vital capacity (FVC) [ Time Frame: measured before and after intervention ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Beta endorphin [ Time Frame: before and after intervention ] [ Designated as safety issue: No ]

Enrollment: 44
Study Start Date: March 2008
Study Completion Date: September 2008
Primary Completion Date: September 2008 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Group 1
Application of Acu-TENS
 Device: Transcutaneous electrical nerve stimulation (TENS)
Placebo Comparator: Group 2 Device: Transcutaneous electrical nerve stimulation (TENS)
Placebo

  Eligibility

Ages Eligible for Study:   45 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • clinical diagnosis with COPD

Exclusion Criteria:

  • allergic to gel
  • unable to perform spirometry
  • unable to communicate
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00922051

Locations
China, Sichuan
West China Hospital
Chengdu, Sichuan, China
Sponsors and Collaborators
The Hong Kong Polytechnic University
Investigators
Principal Investigator: Alice Jones, PhD, FACP The Hong Kong Polytechnic University
  More Information

No publications provided

Responsible Party: Prof. Alice Jones, The Hong Kong Polytechnic University
ClinicalTrials.gov Identifier: NCT00922051     History of Changes
Other Study ID Numbers: HSEARS20070305001
Study First Received: June 16, 2009
Last Updated: June 16, 2009
Health Authority: Hong Kong: Ethics Committee

Keywords provided by The Hong Kong Polytechnic University:
COPD
FEV1
beta endorphin
TENS
acupuncture

Additional relevant MeSH terms:
Lung Diseases
Respiration Disorders
Pulmonary Disease, Chronic Obstructive
Lung Diseases, Obstructive
Respiratory Tract Diseases
 Endorphins
Neurotransmitter Agents
Molecular Mechanisms of Pharmacological Action
Pharmacologic Actions
Physiological Effects of Drugs

ClinicalTrials.gov processed this record on May 16, 2013