Biospecimen Repository for Cardiac Arrhythmias at the Cleveland Clinic

The recruitment status of this study is unknown because the information has not been verified recently.
Verified June 2010 by The Cleveland Clinic.
Recruitment status was  Recruiting
Sponsor:
Information provided by:
The Cleveland Clinic
ClinicalTrials.gov Identifier:
NCT00921986
First received: June 15, 2009
Last updated: June 1, 2010
Last verified: June 2010
  Purpose

The long-term objective of this research is to find genes and biologic pathways causing arrhythmia syndromes and other diseases or conditions. In order to achieve this objective the investigators will collect comprehensive phenotypic data and corresponding blood and/or tissue samples into a biorepository registry of patients, presenting for cardiac arrhythmia evaluation and/or treatment, and control subjects without arrhythmias. This biorepository will be composed of two parts: 1) An Arrhythmia Biorepository of blood and tissue from patients undergoing arrhythmia procedures, cardiac surgery, or inpatient or outpatient evaluations for arrhythmias, and 2) A Collaborative Sample Biorepository for deidentified samples and data from outside institutions and clinical trials.


Condition
Arrhythmias, Cardiac

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective
Official Title: Cleveland Clinic Arrhythmia Biospecimen Repository (Cleveland Clinic Arrhythmia BioBank)

Resource links provided by NLM:


Further study details as provided by The Cleveland Clinic:

Primary Outcome Measures:
  • Various Arrhythmias [ Time Frame: Indefinite ] [ Designated as safety issue: No ]

Biospecimen Retention:   Samples With DNA

Biospecimens to be collected: DNA, RNA, plasma, & serum. Also tissue may be collected.


Estimated Enrollment: 2000
Study Start Date: March 2009
Groups/Cohorts
Arrhythmias
Patients with arrhythmias
Control Subjects
Subjects that do not have a history of cardiac arrhythmias.

Detailed Description:

One time blood draw and follow up in one year.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

Patients undergoing arrhythmia procedures, cardiac surgery or inpatient or outpatient evaluations for arrhythmias at the Cleveland Clinic or from outside collaborative institutions or from other clinical trials.

Criteria

Inclusion Criteria:

  • Male or female at least 18 years old
  • Subjects with a history of or current cardiac arrhythmia, family members of subjects with cardiac arrhythmias, or no cardiac arrhythmia if a Control Subject.

Exclusion Criteria:

  • Subjects previously enrolled in the Arrhythmia BioBank
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00921986

Contacts
Contact: Mina K. Chung, MD 216.444.2290 chungm@ccf.org
Contact: Diana I. Bauer, BS 216.444.9066 bauerd@ccf.org

Locations
United States, Ohio
Cleveland Clinic Foundation Recruiting
Cleveland, Ohio, United States, 44195
Principal Investigator: Mina K. Chung, MD         
Sub-Investigator: David R. Van Wagoner, Ph.D.         
Sub-Investigator: Jonathan D. Smith, Ph.D.         
Sub-Investigator: John Barnard, Ph.D.         
Sponsors and Collaborators
The Cleveland Clinic
Investigators
Principal Investigator: Mina K. Chung, MD The Cleveland Clinic
  More Information

No publications provided

Responsible Party: Mina K. Chung, MD, Cleveland Clinic Foundation
ClinicalTrials.gov Identifier: NCT00921986     History of Changes
Other Study ID Numbers: 09-176
Study First Received: June 15, 2009
Last Updated: June 1, 2010
Health Authority: United States: Institutional Review Board

Keywords provided by The Cleveland Clinic:
genetics
biorepository
cardiac death
atrial fibrillation
ventricular fibrillation
ventricular tachycardia
supraventricular tachycardias
premature ventricular complexes
premature atrial complexes
atrioventricular and intraventricular blocks
sinus node dysfunction
syncope
vasovagal reactivity
postural orthostatic tachycardia syndrome

Additional relevant MeSH terms:
Arrhythmias, Cardiac
Heart Diseases
Cardiovascular Diseases
Pathologic Processes

ClinicalTrials.gov processed this record on September 22, 2014