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Pilot Study of Hippocampal Function in Type 1 Diabetes Mellitus (T1DM) (ASSET)

This study is ongoing, but not recruiting participants.
Sponsor:
Information provided by:
Washington University School of Medicine
ClinicalTrials.gov Identifier:
NCT00918801
First received: June 8, 2009
Last updated: June 9, 2009
Last verified: June 2009
History of Changes
  Purpose

This study is an expansion of a previous study done to determine how thinking skills relate to hypoglycemia (low blood sugar) and certain regions of the brain in children and adolescents. In this study, the investigators are testing thinking skills and measuring brain activity in adolescents with and without type 1 diabetes mellitus.


Condition
Type 1 Diabetes Mellitus

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective
Official Title: Pilot Study of Hippocampal Function in T1DM

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by Washington University School of Medicine:

Enrollment: 91
Study Start Date: April 2007
Estimated Study Completion Date: December 2013
Groups/Cohorts
Type 1 Diabetes Mellitus
Adolescents ages 13-18 with T1DM
Non Controls
Healthy adolescents ages 13-18 without T1DM

  Eligibility

Ages Eligible for Study:   13 Years to 18 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

Young adults will be piloted in a sample of diabetic and non-diabetic adolescents ages 13-18.

Criteria

Inclusion Criteria:

  • Age 13 - 18
  • Right handed
  • Diagnosis of Type 1 Diabetes OR normal sibling control
  • If diabetic, then diagnosis for at least 2 years

Exclusion Criteria:

  • Pregnant or lactating
  • Chronic disease other than well-controlled asthma, or Hashimoto's thyroiditis.
  • Other current serious medical illness
  • Co-morbid psychiatric illness
  • Co-morbid neurological illness
  • Pre-maturity at birth
  • Contraindication to MRI scan
  • orthodontic braces.
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00918801

Locations
United States, Missouri
Washington University School of Medicine
St. Louis, Missouri, United States, 63110
Sponsors and Collaborators
Washington University School of Medicine
Investigators
Principal Investigator: Tamara G Hershey, PhD. Washington University School of Medicine
  More Information

Additional Information:
Link to Dr. Hershey's Web Site  This link exits the ClinicalTrials.gov site

No publications provided

Responsible Party: Tamara G Hershey PhD.,, Washington University School of Medicine
ClinicalTrials.gov Identifier: NCT00918801     History of Changes
Other Study ID Numbers: 06-0786
Study First Received: June 8, 2009
Last Updated: June 9, 2009
Health Authority: United States: Institutional Review Board

Keywords provided by Washington University School of Medicine:
T1DM
MRI

Additional relevant MeSH terms:
Diabetes Mellitus
Diabetes Mellitus, Type 1
Glucose Metabolism Disorders
Metabolic Diseases
 Endocrine System Diseases
Autoimmune Diseases
Immune System Diseases

ClinicalTrials.gov processed this record on May 19, 2013