Prevalence of Coronary Artery Disease in the Siblings of Premature Coronary Heart Disease

The recruitment status of this study is unknown because the information has not been verified recently.
Verified July 2012 by Yonsei University.
Recruitment status was  Recruiting
Sponsor:
Collaborator:
Korean Society of Lipidology and Atherosclerosis
Information provided by (Responsible Party):
Hyuk-Jae Chang, Yonsei University
ClinicalTrials.gov Identifier:
NCT00918242
First received: June 10, 2009
Last updated: July 20, 2012
Last verified: July 2012
  Purpose

The aim of this prospective study is to investigate the prevalence of coronary artery disease using computed tomography with family history of premature coronary heart disease


Condition
Coronary Heart Disease

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Assessment of Occult CAD: Premature CAD Sibling Study (PreCASS)

Resource links provided by NLM:


Further study details as provided by Yonsei University:

Primary Outcome Measures:
  • evaluation of prevalence to coronary artery disease using CT [ Time Frame: within 2 weeks from CT scanning ] [ Designated as safety issue: No ]

Estimated Enrollment: 87
Study Start Date: June 2009
Estimated Primary Completion Date: September 2012 (Final data collection date for primary outcome measure)
  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

the siblings of premature coronary heart disease (male<55years old, female<65yeasrs old: Framingham Heart Study) patients admitted relevant hospital within 1 year

Criteria

Inclusion Criteria:

  • within 1 year
  • the siblings of premature coronary heart disease (male<55years old, female<65yeasrs old: Framingham Heart Study) patients admitted relevant hospital

Exclusion Criteria:

  • Documented coronary heart disease
  • experienced adverse events with relevant treatment
  • contraindicated with beta-blockers
  • Any woman of childbearing potential who is pregnant, seeking to become pregnant or suspects
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00918242

Contacts
Contact: Hyuk-Jae Chang, MD, PhD 82-2-2228-8461 hjchang@yuhs.ac

Locations
Korea, Republic of
Yonsei University Severance Hospital Recruiting
Seoul, Korea, Republic of, 102-752
Contact: Hyuk-Jae Chang, MD    82-2-2228-8454    hjchang@yuhs.ac   
Sponsors and Collaborators
Yonsei University
Korean Society of Lipidology and Atherosclerosis
Investigators
Principal Investigator: Hyuk-Jae Chang, MD, PhD Cardiology Division, Severance Cardiovascular Hospital, Yonsei University College of Medicine
  More Information

Publications:
Responsible Party: Hyuk-Jae Chang, Yonsei University
ClinicalTrials.gov Identifier: NCT00918242     History of Changes
Other Study ID Numbers: 20090616
Study First Received: June 10, 2009
Last Updated: July 20, 2012
Health Authority: Korea: Food and Drug Administration

Keywords provided by Yonsei University:
Coronary Heart Disease
computed tomography
prevalence of coronary artery disease

Additional relevant MeSH terms:
Coronary Artery Disease
Myocardial Ischemia
Coronary Disease
Heart Diseases
Cardiovascular Diseases
Arteriosclerosis
Arterial Occlusive Diseases
Vascular Diseases

ClinicalTrials.gov processed this record on August 21, 2014