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Intensive Care Unit (ICU) Admission Decisions in the Elderly : the ICE-CUB Study (IceCub)

This study has been completed.
Sponsor:
Collaborator:
Institut National de la Santé Et de la Recherche Médicale, France
Information provided by (Responsible Party):
Assistance Publique - Hôpitaux de Paris
ClinicalTrials.gov Identifier:
NCT00912600
First received: June 2, 2009
Last updated: July 25, 2012
Last verified: May 2009
History of Changes
  Purpose

Percentage of patients over 80 admitted in ICU varies greatly from one center to another. ICU admission criteria of older patients are scarcely described and benefit of ICU admission for those patients is uncertain. In this study, we prospectively studied old patients arriving to the emergency department of 15 French hospitals with conditions that potentially warrant ICU admission.The working hypothesis was that ICU admission was associated with a 20% decrease in six-month mortality.


Condition Intervention
Patient Admission
Death
Activities of Daily Living
 Other: Intensive Care Unit admission

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: A Prospective Multicenter Study Examining the Criteria That Determine ICU Admission of Patients Over 80 Who Present to an Emergency Department and Evaluating the Impact of ICU Admission on Short and Mid-term Vital and Functional Outcome

Further study details as provided by Assistance Publique - Hôpitaux de Paris:

Primary Outcome Measures:
  • ICU eligibility as assessed by emergency and ICU physicians [ Time Frame: At the admission ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Hospital death [ Time Frame: During the hospitalisation ] [ Designated as safety issue: Yes ]
  • Change in functional status [ Time Frame: During 6 months ] [ Designated as safety issue: No ]
  • Six-month death [ Time Frame: During 6 months after the end of the hospitalisation ] [ Designated as safety issue: Yes ]

Enrollment: 2643
Study Start Date: November 2004
Study Completion Date: February 2009
Primary Completion Date: January 2006 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
1
Elderly individuals presenting to one of 15 emergency departments and possibly qualifying for admission to an ICU
 Other: Intensive Care Unit admission
Intensive Care Unit admission
Other Name: Intensive Care Unit admission

Detailed Description:

This was a prospective multicenter observational cohort study of elderly individuals presenting to one of 15 emergency departments and possibly qualifying for admission to an ICU. To be included, subjects had to be aged at least 80 years and be diagnosed by the ED physician with one of 74 conditions potentially warranting ICU admission.Outcome studied are ICU eligibility as assessed by emergency and ICU physicians, hospital and six-month death and changes in functional status in the six month following emergency department visit.

  Eligibility

Ages Eligible for Study:   80 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

Old patients arriving to the emergency department of 15 French hospitals with conditions that potentially warrant ICU admission.

Criteria

Inclusion Criteria:

  • Age over 80
  • Be assigned by the emergency physician with one of 74 conditions potentially warranting ICU admission

Exclusion Criteria:

  • Patient's refusal
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00912600

Locations
France
Hôpital Saint-Antoine
Paris, France, 75012
Sponsors and Collaborators
Assistance Publique - Hôpitaux de Paris
Institut National de la Santé Et de la Recherche Médicale, France
Investigators
Principal Investigator: Bertrand GUIDET, MD Assistance Publique - Hôpitaux de Paris
  More Information

No publications provided by Assistance Publique - Hôpitaux de Paris

Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):

Responsible Party: Assistance Publique - Hôpitaux de Paris
ClinicalTrials.gov Identifier: NCT00912600     History of Changes
Other Study ID Numbers: AOR 03 035
Study First Received: June 2, 2009
Last Updated: July 25, 2012
Health Authority: France: French Data Protection Authority

Keywords provided by Assistance Publique - Hôpitaux de Paris:
Intensive Care Units
Triage
Aged, 80 and over
Death
 Activities of Daily Living
Health Services Research
Health Care Quality, Access, and Evaluation

Additional relevant MeSH terms:
Death
Pathologic Processes

ClinicalTrials.gov processed this record on June 18, 2013