Time-Dependent Mobilization of Circulating Progenitor Cells During Strenuous Exercise in Healthy Individuals
Only few data are available on the influence of strenuous exercise on the content of circulating progenitor cells and especially the timeframe of their release. The aim of the present study was to investigate the potential influence of 4 hours of cycling on the time-dependent release of progenitor cells.
|Study Design:||Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Basic Science
|Official Title:||Time Dependent Mobilization of Circulating Progenitor Cells During Strenuous Exercise in Healthy Individuals.|
- Endothelial progenitor cells (EPC) release on [ Time Frame: 4 hours ] [ Designated as safety issue: No ]
|Study Start Date:||September 2008|
|Study Completion Date:||March 2009|
|Primary Completion Date:||March 2009 (Final data collection date for primary outcome measure)|
|Experimental: Exercise Training||
Behavioral: exercise training over 4 hours
Cycling over a period of 4 hours at 70% of max.
Other Name: exercise training
- What is the response of hematopoietic and endothelial progenitor cells after a standardized prolonged endurance exercise?
- What is the kinetic of cell mobilization during this standardized exercise?
|University Leipzig, Heart Center|
|Leipzig, Germany, 04289|
|Study Director:||Gerhard C Schuler, Prof. Dr.||Heart Center Leipzig|