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Comparing Imaginal Exposure and Imagery Rescripting in Treatment of Posttraumatic Stress Disorder (PTSD)

This study is enrolling participants by invitation only.
Sponsor:
Collaborator:
University of Oslo
Information provided by (Responsible Party):
Asle Hoffart, Modum Bad
ClinicalTrials.gov Identifier:
NCT00891098
First received: April 30, 2009
Last updated: October 3, 2011
Last verified: October 2011
History of Changes
  Purpose

The outcome of trauma treatment (Posttraumatic Stress Disorder - PTSD) may be influenced by which emotions that are predominant among current symptoms, e.g. fear, anger, guilt, shame. Different treatment procedures for processing traumatic memories may resolve different emotions. This study compares two different treatment procedures of working with trauma memories in PTSD treatment (namely, Imaginal Exposure and Imagery Rescripting) in order to test this.


Condition Intervention
Posttraumatic Stress Disorder
 Behavioral: Imaginal exposure
Behavioral: Imagery rescripting

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Single Blind (Outcomes Assessor)
Primary Purpose: Treatment
Official Title: Comparing Imaginal Exposure (IE) and Imagery Rescripting and Reprocessing Therapy (IRRT) in the Treatment of Posttraumatic Stress Disorder (PTSD)

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by Modum Bad:

Primary Outcome Measures:
  • PTSD symptoms [ Time Frame: pretreatment, weekly during treatment, posttreatment, followup ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • General psychiatric symptoms [ Time Frame: pretreatment, weekly during treatment, postttreatment, followup ] [ Designated as safety issue: No ]

Estimated Enrollment: 64
Study Start Date: November 2008
Estimated Study Completion Date: November 2012
Estimated Primary Completion Date: November 2012 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Active Comparator: Imaginal exposure Behavioral: Imaginal exposure
7 individual sessions of imaginal exposure of trauma memories according to the prolonged exposure treatment manual
Other Names:
  • prolonged exposure
  • imaginal exposure
  • pe
Experimental: Imagery rescripting Behavioral: Imagery rescripting
7 individual sessions of imagery rescripting of trauma memories according to the imagery rescripting and reprocessing therapy manual
Other Names:
  • rescripting
  • imagery rescripting
  • irrt

Detailed Description:

The main objectives of this study are:

  1. To assess the relative efficacy of the two procedures in inpatient treatment for PTSD
  2. To assess whether the predominant emotions in the traumatic memories moderate the outcome of the different procedures
  3. To assess whether theory-derived constructs mediate outcome and whether the mediating relationships are different in the two treatments
  4. To provide a theoretical account of the two models
  5. To psychometrically evaluate 3 new measures
  Eligibility

Ages Eligible for Study:   20 Years to 65 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • DSM-IV diagnosis of PTSD identified as primary diagnosis
  • Accepts withdrawal of all psychotropic medication

Exclusion Criteria:

  • Extensive dissociative symptoms or current psychosis,
  • Current suicidal risk,
  • Extensive current substance or alcohol abuse, or
  • Ongoing trauma
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00891098

Locations
Norway
Modum Bad
Vikersund, Buskerud, Norway, 3370
Sponsors and Collaborators
Modum Bad
University of Oslo
Investigators
Study Chair: Asle Hoffart, PhD Modum Bad and University of Oslo
  More Information

No publications provided

Responsible Party: Asle Hoffart, phd, Modum Bad
ClinicalTrials.gov Identifier: NCT00891098     History of Changes
Other Study ID Numbers: 2-Hoffart
Study First Received: April 30, 2009
Last Updated: October 3, 2011
Health Authority: Norway:National Committee for Medical and Health Research Ethics

Additional relevant MeSH terms:
Stress Disorders, Post-Traumatic
Stress Disorders, Traumatic
Anxiety Disorders
Mental Disorders

ClinicalTrials.gov processed this record on May 23, 2013