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Treadmill Training and Quality of Life in Parkinson's Disease

This study has been completed.
Sponsor:
Information provided by:
Universidade Federal de Sao Carlos
ClinicalTrials.gov Identifier:
NCT00890669
First received: April 28, 2009
Last updated: May 1, 2009
Last verified: May 2009
  Purpose

Parkinson's disease (PD) causes motor and non-motor impairments that affect the quality of life of the subjects. The purpose was to assess the effects of treadmill walking training with additional body load on the quality of life and motor symptoms of the subjects with PD.

Methods: Nine subjects with PD, Hoehn and Yahr stages 2 through 3, not demented and with capability to ambulate independently voluntarily participate in this study. The training program was divided into three phases (A1-B-A2): treadmill training with additional body load (A1), control condition (conventional physical therapy group) (B) and treadmill training with load again (A2). Each phase lasted six weeks. The quality of life and motor symptoms were assessed by PDQ-39 and UPDRS, respectively. Both evaluations and training were performed during on-phase of the medication cycle.


Condition Intervention
Parkinson's Disease
Other: Treadmill walking training with additional body load

Study Type: Interventional
Study Design: Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Treadmill Walking Training With Additional Body Load Improves Quality of Life in Subjects With Parkinson's Disease

Resource links provided by NLM:


Further study details as provided by Universidade Federal de Sao Carlos:

Primary Outcome Measures:
  • The quality of life was measured through Parkinson Disease Questionnaire (PDQ-39). [ Time Frame: 4 times, once before treatment, and 3 after each treatment phase. ] [ Designated as safety issue: No ]

Enrollment: 9
Study Start Date: August 2007
Study Completion Date: December 2008
Arms Assigned Interventions
Experimental: PD Group
Nine subjects with idiopathic PD, previously diagnosed by one specialist physician participated in this study.
Other: Treadmill walking training with additional body load

The training program was divided into three phases (A1-B-A2):

  • treadmill training with additional body load (A1),
  • control condition (conventional physical therapy group) (B). and
  • treadmill training with additional body load again (A2).

Each phase lasted six weeks, totaling 18 weeks. Both evaluations and training were performed during on-phase of the medication cycle.


  Eligibility

Ages Eligible for Study:   51 Years to 81 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Hoehn and Yahr (H-Y) stages 2 through 3
  • Absence of dementia (Mini-Mental Status Examination - MMSE, defined according to educational level)
  • Capacity to ambulate independently for at least 10 meters

Exclusion Criteria:

  • Change medication (dopaminergic) during the study period
  • Use treadmill for at least six months prior to the study
  • Other neurologic problems or musculoskeletal, cardiovascular and respiratory disease or uncorrected visual deficit that could represent risk and interfere in the accomplishment of the training
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00890669

Locations
Brazil
Universidade Federal de São Carlos
São Carlos, SP, Brazil, 13565-905
Sponsors and Collaborators
Universidade Federal de Sao Carlos
Investigators
Principal Investigator: Nadiesca T Filippin, MSc Universidade Federal de Sao Carlos
Study Chair: Rosana Mattioli, PhD Universidade Federal de Sao Carlos
Study Director: Paula H Lobo da Costa, PhD Universidade Federal de Sao Carlos
  More Information

No publications provided

Responsible Party: Nadiesca Taisa Filippin, Universidade Federal de São Carlos
ClinicalTrials.gov Identifier: NCT00890669     History of Changes
Other Study ID Numbers: 234/07, CEP/UFSCar
Study First Received: April 28, 2009
Last Updated: May 1, 2009
Health Authority: Brazil: Ethics Committee

Keywords provided by Universidade Federal de Sao Carlos:
treadmill training
body load
quality of life
Parkinson's disease
Motor Symptoms

Additional relevant MeSH terms:
Parkinson Disease
Basal Ganglia Diseases
Brain Diseases
Central Nervous System Diseases
Movement Disorders
Nervous System Diseases
Neurodegenerative Diseases
Parkinsonian Disorders

ClinicalTrials.gov processed this record on November 24, 2014