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The Role of High Resolution-Computed Tomography (CT) in Tuberculosis (TB) Outbreak Investigation

This study has been completed.
Sponsor:
Information provided by:
Armed Forces Capital Hospital, Republic of Korea
ClinicalTrials.gov Identifier:
NCT00889759
First received: April 28, 2009
Last updated: September 22, 2009
Last verified: September 2009
History of Changes
  Purpose

The aim of this study is to evaluate the role of high-resolution computed tomography of the chest (HRCT) in the investigation of an outbreak of TB that developed in the South Korean army.


Condition
Tuberculosis

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: The Role of Addition of High Resolution-CT in Outbreak Investigation of Tuberculosis

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by Armed Forces Capital Hospital, Republic of Korea:

Enrollment: 92
Study Start Date: December 2007
Study Completion Date: April 2009
Primary Completion Date: January 2009 (Final data collection date for primary outcome measure)
Detailed Description:

Outbreak investigation including tuberculin skin test (TST), QuantiFERON® TB Gold In-Tube (QFT), and simple chest radiography (CXR) will be performed. For participants with any abnormal findings in these tests, HRCT will be carried out. Active pulmonary TB is diagnosed based on sputum studies or HRCT findings. In addition, participants with positive results both in TST and QTF will be treated as having a latent TB infection (LTBI). TST and QTF were repeated in participants with positive result in one of these tests. CXR will be repeated in all participants at 3 and 6 months of follow-up.

  Eligibility

Genders Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

A military unit in South Korean Army

Criteria

Inclusion Criteria:

  • All soldiers who assigned to the military battery where a tuberculosis outbreak occurred

Exclusion Criteria:

  • Soldiers who could not complete study
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00889759

Sponsors and Collaborators
Armed Forces Capital Hospital, Republic of Korea
Investigators
Principal Investigator: Jae-Joon Yim, MD Seoul National University Hospital
  More Information

No publications provided

Responsible Party: Sei Won Lee/Division chief of pulmonology, Armed Forces Capital Hospital
ClinicalTrials.gov Identifier: NCT00889759     History of Changes
Other Study ID Numbers: TBoutbreak
Study First Received: April 28, 2009
Last Updated: September 22, 2009
Health Authority: Korea: Food and Drug Administration

Keywords provided by Armed Forces Capital Hospital, Republic of Korea:
Tuberculosis
Outbreaks

Additional relevant MeSH terms:
Tuberculosis
Mycobacterium Infections
Actinomycetales Infections
Gram-Positive Bacterial Infections
Bacterial Infections

ClinicalTrials.gov processed this record on May 23, 2013