Protocol to Obtain Blood Samples for Leukemia Research
The purpose of this study is to collect a blood sample in patients with Chronic Lymphocytic Leukemia (CLL).
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Protocol to Obtain Blood Samples for Leukemia Research|
- To determine the frequency with which CLL cells incubated ex vivo with vincristine undergo rapid interphase apoptosis. [ Time Frame: 2 Years ] [ Designated as safety issue: No ]
- To determine whether suppression or inhibition of BCL2 family members can acutely sensitize CLL cells to vincristine. [ Time Frame: 2 Years ] [ Designated as safety issue: No ]
Biospecimen Retention: Samples With DNA
10cc of peripheral blood.
|Study Start Date:||April 2009|
|Estimated Study Completion Date:||April 2015|
|Estimated Primary Completion Date:||April 2015 (Final data collection date for primary outcome measure)|
Other: No Intervention
Patients with Chronic Lymphocytic Leukemia (CLL)
Other Name: No Intervention
The blood sample will be used in the laboratory to perform studies focusing on Chronic Lymphocytic Leukemia (CLL).
Please refer to this study by its ClinicalTrials.gov identifier: NCT00889031
|United States, New Hampshire|
|Dartmouth-Hitchcock Medical Center|
|Lebanon, New Hampshire, United States, 03756|
|Principal Investigator:||Christopher H Lowrey, MD||Dartmouth-Hitchcock Medical Center|